Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.68 |
| ▸ | IAPP | P10997 | 4/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | GUSB | P08236 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471832 | 0.91 | BCHE (0.77) | BACE1NR1H4IAPPBCHEGUSB | |
| SCHEMBL1159948 | 0.90 | BACE1 (0.61) | BACE1NR1H4IAPPBCHEGUSB | |
| SCHEMBL11360766 | 0.87 | BACE1 (0.62) | BACE1NR1H4IAPPBCHEGUSB | |
| SCHEMBL11360764 | 0.87 | BACE1 (0.62) | BACE1NR1H4IAPPBCHEGUSB | |
| SCHEMBL9693070 | 0.85 | BACE1 (0.61) | BACE1NR1H4IAPPBCHEGUSB | |
| SCHEMBL4970085 | 0.82 | BACE1 (0.64) | BACE1NR1H4IAPPCHRNA7MAPT | |
| SCHEMBL7861935 | 0.81 | NR1H4 (0.74) | BACE1NR1H4CYP1A1CYP1B1MAOB | |
| SCHEMBL1073514 | 0.81 | IAPP (0.62) | BACE1IAPPBCHEGUSBCYP1B1 | |
| SCHEMBL7925826 | 0.81 | IAPP (0.62) | BACE1IAPPBCHEGUSBCYP1B1 | |
| SCHEMBL30872967 | 0.81 | IAPP (0.62) | BACE1IAPPBCHEGUSBCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108498412-B | Fat-soluble glabridin compound whitening agent and application thereof | 亿利耐雀生物科技有限公司 | 2021-07-09 | — | — | CN | claimed |
| WO-2021053513-A1 | METHODS AND MICROORGANISMS FOR PRODUCING FLAVONOIDS | ELESZTO GENETIKA, INC. (US) | 2021-03-25 | — | — | WO | claimed |
| EP-2875359-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | Charles R Drew University of Medicine and Science (US) | 2015-05-27 | — | — | EP | claimed |
| WO-2013149258-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | Charles Drew University of Medicine and Science (US) | 2013-10-03 | — | — | WO | claimed |
| US-8367121-B2 | Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease | FLORIDA A & M UNIVERSITY (US) | 2013-02-05 | — | — | US | claimed |
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | claimed |
| US-20100150895-A1 | Nutraceutical agent for attenuating the Neurodegenerative process associated with Parkinson's disease | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-06-17 | — | — | US | claimed |
| EP-2027279-A2 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | Libragen (FR) | 2009-02-25 | — | — | EP | claimed |
| US-20080292607-A1 | Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease | MAZZIO ELIZABETH | 2008-11-27 | — | — | US | claimed |
| WO-2007144368-A2 | WATER SOLUBLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS | LIBRAGEN (FR) | 2007-12-21 | — | — | WO | claimed |
| US-20070208087-A1 | Compounds, compositions and methods for the treatment of inflammatory diseases | PROTEOTECH INC. | 2007-09-06 | — | — | US | claimed |
| US-20070116779-A1 | Comprehensive nutraceutical agent for treatment/ prevention of Parkinson's disease | MAZZIO ELIZABETH | 2007-05-24 | — | — | US | claimed |
| US-20050289662-A1 | Reporter system for plants | ARESA BIODETECTION APS (DK) | 2005-12-29 | — | — | US | claimed |
| EP-1511847-A1 | REPORTER SYSTEM FOR PLANTS | Aresa Biodetection Aps (DK) | 2005-03-09 | — | — | EP | claimed |
| WO-2003100068-A1 | REPORTER SYSTEM FOR PLANTS | ARESA BIODETECTION APS (DK) | 2003-12-04 | — | — | WO | claimed |
| WO-2003013554-A2 | AROMATASE INHIBITORS FROM BROUSSONETIA PAPYRIFERA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2003-02-20 | — | — | WO | claimed |
| US-5109025-A | Use of 2',3,4,4'-tetrahydroxychalcone (butein) | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-28 | — | — | US | claimed |
| CN-119432884-A | Polygonatum cyrtonema PcOMT gene and application thereof in promotion of high isoflavone synthesis and methylation | 浙江农林大学 | 2025-02-14 | — | — | CN | disclosed |
| US-5109025-A | Use of 2',3,4,4'-tetrahydroxychalcone (butein) | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-28 | — | — | US | disclosed |
| EP-0399051-A1 | POLYVALENT ANTIINFLAMMATORY AGENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208087-A1 | Compounds, compositions and methods for the treatment of inflammatory diseases | NR1H2, NR1H3, NR1H4 | BACE1 455/4885NR1H4 3/4885IAPP 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.