Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.77 |
| ▸ | GUSB | P08236 | 1/20 | 0.77 |
| ▸ | BACE1 | P56817 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 6/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | IAPP | P10997 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636137 | 0.91 | BACE1 (0.74) | BCHEGUSBBACE1MAOBAR | |
| SCHEMBL11360764 | 0.89 | BACE1 (0.62) | BCHEGUSBBACE1MAOBAR | |
| SCHEMBL11360766 | 0.89 | BACE1 (0.62) | BCHEGUSBBACE1MAOBAR | |
| SCHEMBL660339 | 0.87 | BCHE (1.00) | BCHEGUSBMAOBARCHRNA7 | |
| SCHEMBL130475 | 0.87 | BCHE (1.00) | BCHEGUSBMAOBARCHRNA7 | |
| SCHEMBL9693070 | 0.87 | BACE1 (0.61) | BCHEGUSBBACE1MAOBAR | |
| SCHEMBL5138170 | 0.84 | MAOB (0.82) | BCHEGUSBMAOBARNR1H4 | |
| SCHEMBL5138171 | 0.84 | MAOB (0.82) | BCHEGUSBMAOBARNR1H4 | |
| SCHEMBL7925826 | 0.83 | IAPP (0.62) | BCHEGUSBBACE1MAOBMAPT | |
| SCHEMBL1073514 | 0.83 | IAPP (0.62) | BCHEGUSBBACE1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190008797-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-01-10 | — | — | US | claimed |
| WO-2017132135-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-03 | — | — | WO | claimed |
| EP-2875359-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | Charles R Drew University of Medicine and Science (US) | 2015-05-27 | — | — | EP | claimed |
| WO-2013149258-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | Charles Drew University of Medicine and Science (US) | 2013-10-03 | — | — | WO | claimed |
| US-20110288161-A1 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER | 2011-11-24 | — | — | US | claimed |
| US-20110104305-A1 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | DAY BRIAN J | 2011-05-05 | — | — | US | claimed |
| EP-2217259-A2 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | National Jewish Health (US) | 2010-08-18 | — | — | EP | claimed |
| WO-2009052411-A2 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER (US) | 2009-04-23 | — | — | WO | claimed |
| US-20080221029-A1 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-09-11 | — | — | US | claimed |
| EP-1954681-A2 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | National Jewish Medical and Research Center (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007073518-A9 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | NAT JEWISH MED & RES CENTER (US) | 2007-08-23 | — | — | WO | claimed |
| WO-2007073518-A2 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER (US) | 2007-06-28 | — | — | WO | claimed |
| US-20060135585-A1 | Compounds and methods for thiol-containing compound efflux and cancer treatment | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER (US) | 2006-06-22 | — | — | US | claimed |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| US-20240373850-A1 | Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. | PONTIFICIA UNIV CATOLICA DE VALPARAISO (CL) | 2024-11-14 | — | — | US | disclosed |
| WO-2003072790-A2 | PRODUCTION OF DADZEIN IN TRANSGENIC PLANTS | UNILEVER PLC (GB) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003006987-A9 | METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES | SALK INST FOR BIOLOGICAL STUDI (US) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003006987-A1 | METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2003-01-23 | — | — | WO | disclosed |
| EP-0370461-A2 | Chalcone derivatives and process for producing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135585-A1 | Compounds and methods for thiol-containing compound efflux and cancer treatment | ABCC1, ABCC2, ABCB1 | BCHE 2681/4885GUSB 681/4885BACE1 4576/4885 |
| US-20240373850-A1 | Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. | ERG28, RXFP4, CROCC | BCHE 13/4885GUSB 2796/4885BACE1 2836/4885 |
| US-20080221029-A1 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | ABCC1, SLC47A2, SLC47A1 | BCHE 1566/4885GUSB 924/4885BACE1 3161/4885 |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | BCHE 588/4885GUSB 1374/4885BACE1 712/4885 |
| US-20190008797-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | ESRRG, GPER1, ESR2 | BCHE 948/4885GUSB 1267/4885BACE1 2046/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | BCHE 465/4885GUSB 1171/4885BACE1 1486/4885 |
| US-20110288161-A1 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | ABCC1, SLC47A2, SLC47A1 | BCHE 1566/4885GUSB 924/4885BACE1 3161/4885 |
| US-20110104305-A1 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | ABCC1, ABCC2, ABCB1 | BCHE 2681/4885GUSB 681/4885BACE1 4576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.