SCHEMBL497034

SCHEMBL497034

C1=C(N2CCCC2)CCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
PSMB1 P20618 1/20 0.33
PSMB5 P28074 1/20 0.33
USP2 O75604 2/20 0.32
INMT O95050 1/20 0.32
NPSR1 Q6W5P4 3/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 2/20 0.31
GAA P10253 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
LMNA P02545 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM1A O60341 1/20 0.31
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
MEN1 O00255 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5111613 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL6699994 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL14818806 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL23661069 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL8992014 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL23486255 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL8420655 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL497507 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL11110396 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2
SCHEMBL8992009 0.98 ALDH1A1 (0.35) MAPTALDH1A1PSMB1PSMB5USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509598-B2 Process solution composition for polymer treatment comprising a fluorine compound, a ketone solvent, and a polar aprotic solvent DONGWOO FINE-CHEM CO., LTD. (KR) 2025-12-30 US claimed
EP-4479487-A1 SOLUBLE WATER SCAVENGER MOLECULES FOR USE WITH DIELECTRIC FLUIDS General Electric Technology GmbH (CH) 2024-12-25 EP claimed
CN-118165259-A Waterborne polyurethane, preparation method thereof, expansion type steel structure fireproof coating containing waterborne polyurethane and transparent facing type fireproof coating 山西省建筑科学研究院集团有限公司 2024-06-11 CN claimed
CN-118165251-A Nonionic type double-amino hydrophilic chain extender and preparation method thereof, and nonionic type water-based non-isocyanate polyurethane and preparation method thereof 山西省建筑科学研究院集团有限公司 2024-06-11 CN claimed
CN-118165260-A Waterborne polyurethane, preparation method thereof, expansion type steel structure fireproof coating containing waterborne polyurethane and transparent facing type fireproof coating 山西省建筑科学研究院集团有限公司 2024-06-11 CN claimed
CN-117417245-A Method for synthesizing ketoprofen through pyrolytic aromatization reaction 复旦大学 2024-01-19 CN claimed
WO-2023156969-A1 SOLUBLE WATER SCAVENGER MOLECULES FOR USE WITH DIELECTRIC FLUIDS GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2023-08-24 WO claimed
US-20230265349-A1 SOLUBLE WATER SCAVENGER MOLECULES FOR USE WITH DIELECTRIC FLUIDS GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2023-08-24 US claimed
US-20220119569-A1 Curable and Solvent Soluble Formulations and Methods of Making and Using Therof POLY6 TECHNOLOGIES, INC. 2022-04-21 US claimed
CN-112586583-A Low-fat low-sugar high-protein chocolate product and preparation method thereof 安徽兆龙食品有限公司 2021-04-02 CN claimed
WO-2004078708-A2 NOVEL METHOD FOR SYNTHESISING DERIVATIVES OF (2S, 3AS, 7AS)-1-[(S)-ALANYL]-OCTAHYDRO,-IH-INDOLE-2-CARBOXYLIC ACID AND THE USE THEREOF FOR PERINDOPRIL SYNTHESIS LES LABORATOIRES SERVIER (FR) 2004-09-16 WO claimed
WO-2004078707-A2 NOVEL METHOD FOR SYNTHESISING (2S, 3AS, 7AS)-PERHYDROINDOLE-2-CARBOXYLIC ACID AND THE ESTERS THEREOF AND THE USE THEREOF FOR PERINDOPRIL SYNTHESIS LES LABORATOIRES SERVIER (FR) 2004-09-16 WO claimed
WO-2004078107-A2 NOVEL METHOD FOR SYNTHESISING PERINDOPRIL AND THE PHARMACEUTICALLY ACCEPTABLE SALT THEREOF LES LABORATOIRES SERVIER (FR) 2004-09-16 WO claimed
EP-1455736-A1 RESTRUCTURING AND FINISHING OF KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-09-15 EP claimed
EP-1403275-A1 Process for the synthesis of perindopril and its pharmaceutically acceptable salts Les Laboratoires Servier (FR) 2004-03-31 EP claimed
EP-1403277-A1 Method for synthesis of (2S,3aS,7aS)-1-((S)-alanyl)-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril LES LABORATOIRES SERVIER (FR) 2004-03-31 EP claimed
EP-1338591-A1 Method for synthesis of (2S,3aS,7aS)-perhydroindole-2- carboxylic acid and esters thereof, and use in the synthesis of perindopril Les Laboratoires Servier (FR) 2003-08-27 EP claimed
WO-2003053375-A1 RESTRUCTURING AND FINISHING OF KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-07-03 WO claimed
US-6153783-A REACTING A CYCLOALKANONE WITH A 2-SUBSTITUTED-1-ALKENE USING AN ENAMINE CATALYST TO PRODUCE A CORRESPONDINGLY SUBSTITUTED INTERMEDIATE; RING OPENING BY ULTRAVIOLET RADIATION AND USING A REACTING SOLVENT COGNIS CORPORATION (US) 2000-11-28 US claimed
US-6086661-A (A)IMIDAZOLINIUM QUATERNARY SALT, (B) PHOSPHONIUM QUATERNARY SALT, OR (C) AN AMMONIUM QUATERNARY SALT; A PAPER-CURL REDUCING COMPOUND; DYE; STABILIZERS, BIOCIDE, WATER SOLUBLE SALT XEROX CORPORATION (US) 2000-07-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509598-B2 Process solution composition for polymer treatment comprising a fluorine compound, a ketone solvent, and a polar aprotic solvent CHRM1, CHRM2, PNMT MAPT 835/4885ALDH1A1 1453/4885PSMB1 1618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.