Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030549 | 0.87 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL3484490 | 0.81 | PNMT (0.54) | PNMTHTR7HTR2BNPC1RAB9A | |
| Bromide SCHEMBL15671137 | 0.81 | PNMT (0.54) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL31757158 | 0.81 | PNMT (0.48) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL2489527 | 0.81 | PNMT (0.48) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL7037299 | 0.81 | PNMT (0.52) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL27861228 | 0.81 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL4970480 | 0.81 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL425742 | 0.80 | PNMT (0.58) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL29892750 | 0.80 | PNMT (0.58) | PNMTHTR7HTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934236-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GlycoMimetics, Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007028050-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GLYCOMIMETICS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |