Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919020 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1KMT2APTGS1ATM | |
| SCHEMBL9232485 | 0.78 | KMT2A (0.44) | KDM4EALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4968654 | 0.77 | POLB (0.37) | ALDH1A1KMT2AATMHTTMEN1 | |
| SCHEMBL15768034 | 0.76 | KMT2A (0.40) | KDM4EALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL1013267 | 0.74 | ITGA4 (0.32) | KDM4EALDH1A1HTT | |
| SCHEMBL15825776 | 0.73 | ATM (0.38) | KDM4EKMT2AATMMEN1LMNA | |
| SCHEMBL9204354 | 0.69 | CYP1A2 (0.44) | KDM4EALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL2015049 | 0.68 | MAPK1 (0.45) | KDM4EALDH1A1KMT2AHTTKAT2B | |
| SCHEMBL619113 | 0.68 | HTT (0.36) | ALDH1A1KMT2AATMHTTKAT2B | |
| SCHEMBL5204576 | 0.68 | TSHR (0.44) | KDM4EALDH1A1HTTKAT2BBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320527-B1 | METHOD FOR PRODUCING 1 SUBSTITUTED 5-CHLORO-4 METHYL PYRAZOLES | BASF SE (DE) | 2008-08-13 | — | — | EP | disclosed |