Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554945 | 0.92 | RAB9A (0.52) | MCHR1GRM5NPC1RAB9A | |
| SCHEMBL28264042 | 0.92 | RAB9A (0.52) | MCHR1GRM5NPC1RAB9A | |
| SCHEMBL27124836 | 0.89 | MCHR1 (0.50) | MCHR1KDM4EUTS2RNPC1RAB9A | |
| SCHEMBL417131 | 0.89 | SMYD3 (0.55) | MCHR1KDM4ESMYD3UTS2R | |
| SCHEMBL31737693 | 0.83 | UTS2R (0.46) | MCHR1KDM4ESMYD3UTS2R | |
| SCHEMBL28300778 | 0.78 | KDM4E (0.44) | MCHR1KDM4ESMYD3UTS2RGRM5 | |
| SCHEMBL3060481 | 0.76 | MCHR1 (0.48) | MCHR1UTS2R | |
| SCHEMBL10211594 | 0.76 | PRKDC (0.45) | MCHR1UTS2RNPC1RAB9APIM1 | |
| SCHEMBL28272930 | 0.75 | — | — | |
| SCHEMBL4532908 | 0.74 | KDM4E (0.67) | KDM4EPIM1MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112272670-B | Di-ring derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |