SCHEMBL4970820

SCHEMBL4970820

NCN(OCCO)OCCO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1038170 0.78 TSHR (0.35) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1720232 0.75 TSHR (0.39) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL6232031 0.75 TSHR (0.39) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL970561 0.74 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL4130583 0.73 TSHR (0.37) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL35604 0.71 ALDH1A1 (0.41) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL28125944 0.71 ALDH1A1 (0.41) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14420467 0.69
SCHEMBL22164162 0.69 TSHR (0.39) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1952750 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384174-B1 None US disclosed
CN-115819710-A Fluorine-containing polyurethane material and preparation method thereof 桂林航天工业学院 2023-03-21 CN disclosed
EP-1143063-B1 Artificial leather DAINICHISEIKA COLOR CHEM (JP) 2008-09-17 EP disclosed
EP-1132378-B1 Fluorine-containing diols and use thereof DAINICHISEIKA COLOR CHEM (JP) 2004-08-04 EP disclosed
US-6555230-B2 Polyurethane base sheet having side chains derived from fluorine containing diols DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2003-04-29 US disclosed
EP-1136278-B1 Donor element for thermal transfer recording DAINICHISEIKA COLOR CHEM (JP) 2003-01-22 EP disclosed
US-6495490-B2 BACK LAYER COMPRISES A POLYURETHANE HAVING SIDE CHAINS DERIVED FROM A FLUORINE-CONTAINING DIOL; SLIPPERINESS, NONTACKY, HEAT RESISTANCE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2002-12-17 US disclosed
US-6384174-B2 POLYURETHANES DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2002-05-07 US disclosed
US-20020041965-A1 Polyurethane base sheet having side chains derived from fluorine containing diols DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2002-04-11 US disclosed
US-20010034413-A1 Fluorine-containing diols and use thereof DAINICHISEIKA COLOR & CHEM. MFG. CO., LTD. (JP) 2001-10-25 US disclosed
US-20010034301-A1 Thermal recording media DAINICHISEIKA COLOR & CHEMICALS MFG. CO. (JP) 2001-10-25 US disclosed
EP-1143063-A2 Artificial leather DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2001-10-10 EP disclosed
EP-1136278-A1 Dye-donor element for thermal transfer recording DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2001-09-26 EP disclosed
EP-1132378-A2 Fluorine-containing diols and use thereof DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2001-09-12 EP disclosed