Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SCN4A | P35499 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 14/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136099 | 0.84 | P2RX4 (0.44) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL21082763 | 0.78 | TLR9 (0.43) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL11163328 | 0.75 | LMNA (0.37) | LMNATSHRMAPK1SCN4ASCN5A | |
| Bromide SCHEMBL11163151 | 0.74 | LMNA (0.36) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL14345598 | 0.72 | LMNA (0.46) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL2607158 | 0.72 | MAPT (0.49) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL12175889 | 0.72 | LMNA (0.52) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL12959709 | 0.72 | LMNA (0.46) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL5894542 | 0.70 | LMNA (0.41) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL5375186 | 0.70 | LMNA (0.41) | LMNATSHRMAPK1SCN4ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981478-A2 | CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS | Regents of the University of Colorado (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007084541-A2 | CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS | REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2007-07-26 | — | — | WO | disclosed |