⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965604 | 0.85 | — | — | |
| SCHEMBL49271 | 0.85 | — | — | |
| SCHEMBL10012991 | 0.82 | CES2 (0.61) | — | |
| SCHEMBL49329 | 0.82 | — | — | |
| SCHEMBL304518 | 0.82 | CES2 (0.61) | — | |
| SCHEMBL472301 | 0.82 | CES2 (0.61) | — | |
| SCHEMBL5185648 | 0.82 | CES2 (0.61) | — | |
| SCHEMBL5697616 | 0.78 | GLA (0.46) | — | |
| SCHEMBL15477012 | 0.77 | — | — | |
| SCHEMBL7611619 | 0.77 | MEN1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1010 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265602-A2 | LEOLIGIN DERIVATIVES AS PROLIFERATION INHIBITORS OF SMOOTH MUSCLE CELLS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2023-10-25 | — | — | EP | claimed |
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | claimed |
| CN-115850328-A | Diphosphine ligand with cyclopropane skeleton and cobalt complex thereof, preparation method and application | 南开大学 | 2023-03-28 | — | — | CN | claimed |
| US-20220162219-A1 | Chiral Bisamino-Ether Compounds, And Method of Preparation and Use Thereof | UNIV JINAN (CN) | 2022-05-26 | — | — | US | claimed |
| CN-114249725-A | Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof | 南开大学 | 2022-03-29 | — | — | CN | claimed |
| CN-114014878-A | Novel conjugated alkenyl zinc reagent, preparation method and application thereof | 南开大学 | 2022-02-08 | — | — | CN | claimed |
| CN-106518931-B | Novel iridium complex of spiro phosphine-carboxylic acid and preparation method and application thereof | 南开大学 | 2021-08-24 | — | — | CN | claimed |
| US-10961220-B2 | Method for preparing substituted imidazolyl carboxyamides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-03-30 | — | — | US | claimed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | claimed |
| EP-3728214-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2020-10-28 | — | — | EP | claimed |
| WO-1999033462-A1 | 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1999-07-08 | — | — | WO | claimed |
| US-5889043-A | Taxoids, preparation thereof and pharmaceutical Compositions containing same | RHONE-POULENC RORER S.A. (FR) | 1999-03-30 | — | — | US | claimed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | claimed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | claimed |
| EP-0817780-A1 | NOVEL TAXOIDS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1998-01-14 | — | — | EP | claimed |
| WO-1996030356-A1 | NOVEL TAXOIDS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1996-10-03 | — | — | WO | claimed |
| EP-0653427-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-05-17 | — | — | EP | claimed |
| EP-0237341-B1 | MACROLIDE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-09-22 | — | — | EP | claimed |
| US-4978675-A | Pesticides | AMERICAN CYANAMID COMPANY (US) | 1990-12-18 | — | — | US | claimed |
| EP-0237341-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-16 | — | — | EP | claimed |