Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472301 | 1.00 | CES2 (0.61) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL49329 | 1.00 | — | — | |
| SCHEMBL10012991 | 1.00 | CES2 (0.61) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL304518 | 1.00 | CES2 (0.61) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL501747 | 1.00 | CES2 (0.61) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL49271 | 0.97 | — | — | |
| SCHEMBL965604 | 0.90 | — | — | |
| SCHEMBL49712 | 0.82 | — | — | |
| Bicarbonate SCHEMBL28260429 | 0.78 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL11839162 | 0.76 | CES2 (1.00) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892602-A1 | METHOD FOR THE PREPARATION OF DEUTERATED OR TRITIATED COMPOUNDS | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2021-10-13 | — | — | EP | disclosed |
| EP-2478981-B1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-9704612-B2 | Composition of silver-conjugated compound composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-07-11 | — | — | US | disclosed |
| US-9412487-B2 | Silver-(conjugated compound) composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-2822924-A1 | METHOD FOR SYNTHESISING AMINOBIPHENYLS USING ARYL HYDRAZINES | BASF SE (DE) | 2015-01-14 | — | — | EP | disclosed |
| EP-2683682-A1 | PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE | BASF SE (DE) | 2014-01-15 | — | — | EP | disclosed |
| US-20140001422-A1 | COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| US-20130338369-A1 | Process for the Synthesis of Aminobiphenylene | BASF SE (DE) | 2013-12-19 | — | — | US | disclosed |
| WO-2013132006-A1 | METHOD FOR SYNTHESISING AMINOBIPHENYLS USING ARYL HYDRAZINES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2013-09-12 | — | — | WO | disclosed |
| EP-2546229-A1 | Method for synthesising aminobiphenyls | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2013-01-16 | — | — | EP | disclosed |
| US-20070208165-A1 | Process for the preparation of benzotriazoles | FISCHER WALTER | 2007-09-06 | — | — | US | disclosed |
| US-20040019220-A1 | Process for the preparation of benzotriazoles | CIBA SPECIALTY CHEMICALS CORP. | 2004-01-29 | — | — | US | disclosed |
| CN-1461300-A | Process for preparing benzotriazoles | CIBA SC HOLDING AG (CH) | 2003-12-10 | — | — | CN | disclosed |
| EP-1339700-A1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002024668-A1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-03-28 | — | — | WO | disclosed |
| US-5932642-A | Cyclic phosphinic acid derivatives as stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0850946-A1 | Cyclic phosphinic acid derivatives as stabilizers | Ciba SC Holding AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| EP-0483851-B1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | MITSUBISHI CHEM CORP (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5128350-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0483851-A1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | Mitsubishi Chemical Corporation (JP) | 1992-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208165-A1 | Process for the preparation of benzotriazoles | CBR1, CCNT1, CYP1B1 | CES2 1169/4885CES1 2169/4885HDAC8 1096/4885 |
| US-20130338369-A1 | Process for the Synthesis of Aminobiphenylene | DHPS, DDC, AASDHPPT | CES2 1351/4885CES1 4088/4885HDAC8 3481/4885 |
| US-20040019220-A1 | Process for the preparation of benzotriazoles | SULT1E1, SULT1A1, CYP1B1 | CES2 792/4885CES1 1930/4885HDAC8 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.