SCHEMBL4971920

SCHEMBL4971920

Nc1ccn([C@H]2C[C@H](O)[C@@H](COCO)O2)c(=O)n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.66
P2RY2 P41231 3/20 0.54
P2RY4 P51582 3/20 0.54
P2RY6 Q15077 2/20 0.54
LMNA P02545 3/20 0.51
PDE3A Q14432 3/20 0.51
CACNA1F O60840 2/20 0.51
ALB P02768 2/20 0.51
MAPT P10636 2/20 0.51
CACNA1D Q01668 2/20 0.51
CACNA1S Q13698 2/20 0.51
CACNA1C Q13936 2/20 0.51
ADRB1 P08588 1/20 0.51
DNMT1 P26358 1/20 0.51
THRB P10828 1/20 0.50
MTOR P42345 1/20 0.50
MDM2 Q00987 1/20 0.50
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
PDE4D Q08499 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16359952 0.90 POLB (0.64) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL1962182 0.90 POLB (0.64) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL7772982 0.89 POLB (0.63) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL5666385 0.88 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL3424606 0.88 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL3200090 0.88 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL15617962 0.88 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL1939479 0.88 POLB (0.68) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL8660989 0.87 POLB (0.59) POLBP2RY2P2RY4P2RY6LMNA
SCHEMBL25456568 0.87 POLB (0.67) POLBP2RY2P2RY4P2RY6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605397-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies TETRAGON BIOSCIENCE LTD. (IL) 2026-04-21 US disclosed
EP-4591940-A2 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES Hemispherian AS (NO) 2025-07-30 EP disclosed
EP-4233879-B1 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES HEMISPHERIAN AS (NO) 2025-07-23 EP disclosed
US-20240216415-A1 DEOXY-CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES TETRAGON BIOSCIENCES LTD. (IL) 2024-07-04 US disclosed
US-11963973-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies HEMISPHERIAN AS (NO) 2024-04-23 US disclosed
EP-4233879-A1 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES Hemispherian AS (NO) 2023-08-30 EP disclosed
EP-3917538-B1 DEOXY- CYTIDINE DERIVATIVES FOR USE IN CANCER THERAPIES HEMISPHERIAN AS (NO) 2023-07-12 EP disclosed
US-20220117992-A1 DEOXY-CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES TETRAGON BIOSCIENCES LTD. (IL) 2022-04-21 US disclosed
EP-3917538-A1 DEOXY- CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES Hemispherian AS (NO) 2021-12-08 EP disclosed
WO-2020157335-A1 DEOXY- CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES HEMISPHERIAN AS (NO) 2020-08-06 WO disclosed
US-20080300222-A1 Phosphoantigen Salts Of Organic Bases And Methods For Their Crystallization INNATE PHARMA (FR) 2008-12-04 US disclosed
EP-1933848-A2 PHOSPHOANTIGEN SALTS OF ORGANIC BASES AND METHODS FOR THEIR CRYSTALLIZATION Innate Pharma (FR) 2008-06-25 EP disclosed
WO-2007039635-A2 PHOSPHOANTIGEN SALTS OF ORGANIC BASES AND METHODS FOR THEIR CRYSTALLIZATION INNATE PHARMA (FR) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220117992-A1 DEOXY-CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES UMPS, UPP1, TYMP POLB 272/4885P2RY2 525/4885P2RY4 481/4885
US-20080300222-A1 Phosphoantigen Salts Of Organic Bases And Methods For Their Crystallization HLA-B, LCK, HLA-A POLB 118/4885P2RY2 1413/4885P2RY4 866/4885
US-11963973-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies UMPS, UPP1, TYMP POLB 272/4885P2RY2 525/4885P2RY4 481/4885
US-20240216415-A1 DEOXY-CYTIDINE OR URIDINE DERIVATIVES FOR USE IN CANCER THERAPIES UMPS, UPP1, TYMP POLB 261/4885P2RY2 552/4885P2RY4 518/4885
US-12605397-B2 Deoxy-cytidine or uridine derivatives for use in cancer therapies CDA, DCTD, RNMT POLB 57/4885P2RY2 203/4885P2RY4 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.