SCHEMBL4972042

SCHEMBL4972042

COC(=O)[C@H](COS(=O)(=O)c1ccc(C)cc1)NC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 10/20 0.54
KYNU Q16719 1/20 0.51
CTSK P43235 4/20 0.50
ALDH1A1 P00352 1/20 0.49
ALOX15 P16050 1/20 0.49
CTSL P07711 1/20 0.48
CA5A P35218 1/20 0.48
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3948746 1.00 P2RX7 (0.54) P2RX7KYNUCTSKALDH1A1ALOX15
SCHEMBL3957822 0.92 P2RX7 (0.54) P2RX7CTSKCTSLLMNA
SCHEMBL28450226 0.91 P2RX7 (0.50) P2RX7CTSKCTSLCA5ALMNA
SCHEMBL8932365 0.90 CA1 (0.47) P2RX7CTSKALDH1A1LMNA
SCHEMBL3652008 0.86 P2RX7 (0.51) P2RX7CTSKCA5ALMNA
SCHEMBL3652010 0.86 P2RX7 (0.51) P2RX7CTSKCA5ALMNA
SCHEMBL22552853 0.86 P2RX7 (0.51) P2RX7CTSKCA5ALMNA
SCHEMBL38652164 0.85 P2RX7 (0.55) P2RX7ALDH1A1LMNA
SCHEMBL17471772 0.85 P2RX7 (0.55) P2RX7ALDH1A1LMNA
SCHEMBL7100122 0.84 P2RX7 (0.49) P2RX7ALDH1A1CTSLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024237543-A1 MULTI-FUNCTIONAL PARTICLES FOR NEAR-INFRARED IMAGING GUIDANCE AND PHOTOTHERMAL THERAPY AND COMPOSITE COMPRISING SAME 한양대학교 산학협력단 2024-11-21 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
US-20230173098-A1 NANOPARTICLE COMPLEX FOR ORAL ADMINISTRATION AND USES THEREOF IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2023-06-08 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
US-11369425-B2 Lactoferrin-conjugated nanoparticle complex and use thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-06-28 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-1236715-B1 Process for S-Aryl cysteine HOFFMANN LA ROCHE (CH) 2008-10-15 EP disclosed
EP-1812383-A1 GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF Smithkline Beecham Corporation (US) 2007-08-01 EP disclosed
WO-2006052722-A1 GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF SMITHKLINE BEECHAM CORPORATION (US) 2006-05-18 WO disclosed
EP-0897911-B9 PROCESS FOR PRODUCING CYSTEINE DERIVATIVES KANEKA CORP (JP) 2004-12-01 EP disclosed
US-6765109-B1 FORMATION OF ENANTIOSELECTIVE MATERIAL; REACTING ARYL THIOL AND PROTECTED SERINE DERIVATIVE ROCHE COLORADO CORPORATION 2004-07-20 US disclosed
EP-0897911-B1 PROCESS FOR PRODUCING CYSTEINE DERIVATIVES KANEKA CORP (JP) 2004-06-09 EP disclosed
EP-1236715-A2 Process for S-Aryl cysteine F. HOFFMANN-LA ROCHE AG (CH) 2002-09-04 EP disclosed
US-6229041-B1 COUPLING CYSTEINE WITH COPPER OR COPPER OXIDE TO GENERATE METAL-AMINO COMPLEX, THEN CONTACTING WITH ARYL-HALIDE TO PRODUCE 3-ARYL-CYSTEINE; XENOBIOTIC METABOLIC PATHWAYS; TARGETTING HIV VIRUS F. HOFFMANN-LA ROCHE AG (CH) 2001-05-08 US disclosed
EP-0968997-A2 Process for S-aryl-L-cysteine and derivatives F. HOFFMANN-LA ROCHE AG (CH) 2000-01-05 EP disclosed
US-6011170-A SULFIDING A PROTECTED CYSTEINE DERIVATIVE WITH A MERCAPTAN WHEREIN THE REACTION IS CONDUCTED IN THE PRESENCE OF A BASE AND WATER IN AN ORGANIC REACTION SOLVENT. KANEKA CORPORATION (JP) 2000-01-04 US disclosed
EP-0897911-A1 PROCESS FOR PRODUCING CYSTEINE DERIVATIVES KANEKA CORPORATION (JP) 1999-02-24 EP disclosed