Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972809 | 1.00 | REN (0.43) | RENCYP3A4TSHRCNR1CNR2 | |
| SCHEMBL3963369 | 0.86 | TSHR (0.41) | RENTSHRCNR1CNR2MAPT | |
| SCHEMBL14864959 | 0.86 | REN (0.42) | RENCNR1CNR2 | |
| SCHEMBL2329579 | 0.86 | REN (0.43) | RENCYP3A4CNR1CNR2 | |
| SCHEMBL2329573 | 0.86 | REN (0.43) | RENCYP3A4CNR1CNR2 | |
| SCHEMBL2329575 | 0.86 | REN (0.43) | RENCYP3A4CNR1CNR2 | |
| SCHEMBL12091032 | 0.84 | REN (0.43) | RENCNR1CNR2SMN1; SMN2 | |
| SCHEMBL5616662 | 0.82 | REN (0.54) | RENCYP3A4TSHR | |
| SCHEMBL4968724 | 0.79 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL4968733 | 0.79 | REN (0.56) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |