SCHEMBL497284

SCHEMBL497284

N#Cc1cccc(Sc2ccccc2)c1C#N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.51
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
HPGD P15428 1/20 0.51
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
CYP1A2 P05177 3/20 0.44
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP3A4 P08684 2/20 0.44
MCL1 Q07820 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
AR P10275 2/20 0.40
NSD2 O96028 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13907657 0.86 CYP1A2 (0.52) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL30360760 0.84 CYP1A2 (0.47) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL20510897 0.84 CYP1A2 (0.53) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL11388978 0.84 HPGD (0.51) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL12923348 0.84 CYP1A2 (0.47) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL29669365 0.84 KDM4E (0.62) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL4011637 0.84 KDM4E (0.62) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL9052517 0.84 MAPT (0.43) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL12219720 0.82 SLC22A12 (0.49) KDM4EALDH1A1MAPTHPGDMAOA
SCHEMBL5074837 0.82 ALDH1A1 (0.55) KDM4EALDH1A1MAPTHPGDMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118054087-B Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-07-19 CN claimed
CN-118054087-A Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-05-17 CN claimed
CN-118054087-B Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-07-19 CN disclosed
CN-118054087-A Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-05-17 CN disclosed
US-20230145826-A1 FLUORESCENT LABELING AGENT AND FLUORESCENT DYE TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-05-11 US disclosed
US-20230145826-A1 FLUORESCENT LABELING AGENT AND FLUORESCENT DYE TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-05-11 US disclosed
CN-115335489-A Fluorescent labeling agent and fluorescent dye 东洋油墨SC控股株式会社 2022-11-11 CN disclosed
US-8105431-B2 Subphthalocyanine derivative having phosphorus derivative as axially substituted group, method for manufacturing the same and optical film using the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2012-01-31 US disclosed
EP-2184328-B1 Subphthalocyanine derivative having phosphorus derivative as axially substituted group, method for manufacturing the same and optical film using the same ORIENT CHEMICAL IND (JP) 2011-04-27 EP disclosed
EP-2184328-A2 Subphthalocyanine derivative having phosphorus derivative as axially substituted group, method for manufacturing the same and optical film using the same Orient Chemical Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100036134-A1 Subphthalocyanine derivative having phosphorus derivative as axially substituted group, method for manufacturing the same and optical film using the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-11 US disclosed
US-5703229-A ALUMINUM PHTHALOCYANINE SUBSTITUTED WITH POLYESTER REACTIVE GROUPS; TAGGING THERMOPLASTIC WASTES FOR RECYCLING EASTMAN CHEMICAL COMPANY (US) 1997-12-30 US disclosed
US-5674891-A ANALGESICS WITH SIDE EFFECT REDUCTION THE PROCTER & GAMBLE COMPANY (US) 1997-10-07 US disclosed
US-5525516-A DISSOLVING NEAR INFRARED FLUORESCING COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 1996-06-11 US disclosed
WO-1996010620-A1 METHOD FOR TAGGING PETROLEUM PRODUCTS EASTMAN CHEMICAL COMPANY (US) 1996-04-11 WO disclosed
US-5461136-A Thermoplastic condensation polymer having copolymerized therein one or more near infrared fluorescing compounds EASTMAN CHEMICAL COMPANY (US) 1995-10-24 US disclosed
US-5397819-A Phthalocyanines, naphthalocyanines, sqarines; detectable when exposed to specified wavelength limits of electromagnetic radiation; recycling of wastes EASTMAN CHEMICAL COMPANY (US) 1995-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100036134-A1 Subphthalocyanine derivative having phosphorus derivative as axially substituted group, method for manufacturing the same and optical film using the same PHLPP1, PHLPP2, PROX1 KDM4E 960/4885ALDH1A1 2218/4885MAPT 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.