SCHEMBL30360760

SCHEMBL30360760

Cc1ccc(Sc2cccc(C#N)c2C#N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.47
CYP3A4 P08684 5/20 0.47
CYP2C9 P11712 4/20 0.47
CYP2C19 P33261 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 3/20 0.47
MCL1 Q07820 2/20 0.43
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
AR P10275 3/20 0.40
DHFR P00374 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
HPGD P15428 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
CYP2D6 P10635 3/20 0.37
HTR1A P08908 2/20 0.37
HTR3A P46098 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12923348 1.00 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL17612235 0.90 L3MBTL1 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL497284 0.84 KDM4E (0.51) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL20591218 0.84 CYP1A2 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL20510897 0.83 CYP1A2 (0.53) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL11388978 0.83 HPGD (0.51) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL9644772 0.83 DHFR (0.43) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL5074845 0.82 L3MBTL1 (0.45) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL2075358 0.82 L3MBTL1 (0.42) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E
SCHEMBL13907657 0.82 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed