Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.88 |
| ▸ | TP53 | P04637 | 4/20 | 0.88 |
| ▸ | LMNA | P02545 | 2/20 | 0.88 |
| ▸ | MEN1 | O00255 | 10/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.76 |
| ▸ | POLB | P06746 | 4/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.65 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.65 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.65 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973398 | 1.00 | MAPT (0.88) | MAPTTP53LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1963370 | 0.99 | MAPT (0.86) | MAPTTP53LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1963371 | 0.99 | MAPT (0.86) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL1963685 | 0.91 | MEN1 (0.88) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL1963682 | 0.91 | MEN1 (0.88) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL6098875 | 0.89 | MAPT (0.71) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL6098584 | 0.89 | MAPT (0.71) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL1961879 | 0.83 | MEN1 (0.87) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL1961880 | 0.83 | MEN1 (0.87) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL1961886 | 0.82 | MAPT (0.84) | MAPTTP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| EP-1954283-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | Hydra Biosciences, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007056124-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | MAPT 1751/4885TP53 4750/4885LMNA 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.