Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 11/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109040 | 0.86 | MAPT (0.69) | L3MBTL1EPHX2KMT2AALDH1A1MAPT | |
| SCHEMBL1187952 | 0.85 | L3MBTL1 (0.77) | L3MBTL1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL11244018 | 0.84 | MAPT (0.57) | L3MBTL1EPHX2KMT2AALDH1A1MAPT | |
| SCHEMBL6442057 | 0.83 | L3MBTL1 (0.48) | L3MBTL1CNR1EPHX2KMT2AALDH1A1 | |
| SCHEMBL4972267 | 0.83 | KCNQ2 (0.60) | L3MBTL1CNR1EPHX2ALDH1A1MAPT | |
| SCHEMBL6389065 | 0.80 | MAPT (0.53) | L3MBTL1CNR1KMT2AALDH1A1MAPT | |
| SCHEMBL793743 | 0.80 | KMT2A (0.70) | L3MBTL1CNR1EPHX2KMT2AMAPT | |
| SCHEMBL14349951 | 0.79 | RAB9A (0.58) | L3MBTL1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL11047592 | 0.79 | L3MBTL1 (0.68) | L3MBTL1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL989005 | 0.78 | SMN1; SMN2 (0.60) | L3MBTL1CNR1EPHX2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606247-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. Lundbeck A/S (DK) | 2005-12-21 | — | — | EP | claimed |
| WO-2004080950-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-23 | — | — | WO | claimed |
| EP-1983974-A1 | USE OF KCNQ-OPENERS FOR TREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA | H. Lundbeck A/S (DK) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007090409-A1 | USE OF KCNQ-OPENERS FOR THREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA | H. LUNDBECK A/S (DK) | 2007-08-16 | — | — | WO | disclosed |
| EP-1606247-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. Lundbeck A/S (DK) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080950-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |