Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL497430

CC(C)CC(=O)OCCO.N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
PRKCA P17252 3/20 0.40
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.37
PRKD3 O94806 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCI P41743 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36
PRKCZ Q05513 1/20 0.36
PRKCD Q05655 1/20 0.36
PRKD1 Q15139 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2529389 0.98 MMP1 (0.42) MMP1MMP2MMP3MMP9MMP13
Ethylene Glycol SCHEMBL27981937 0.95 MMP1 (0.41) MMP1MMP2MMP3MMP9MMP13
SCHEMBL27293683 0.95 MMP1 (0.41) MMP1MMP2MMP3MMP9MMP13
SCHEMBL27981945 0.95 MMP1 (0.41) MMP1MMP2MMP3MMP9MMP13
Ethylene Glycol SCHEMBL27981930 0.93 MMP1 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18378814 0.85 MMP1 (0.46) MMP1MMP2MMP3MMP9MMP13
SCHEMBL27568673 0.85 MEN1 (0.44) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2529030 0.84 MMP1 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18730849 0.84 TSHR (0.38) PRKCAALDH1A1TSHRMGLL
SCHEMBL2531293 0.83 NAAA (0.41) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8105500-B2 Slurry rheology modifier KAO CORPORATION (JP) 2012-01-31 US disclosed
US-20080300341-A1 SLURRY RHEOLOGY MODIFIER YAMAMURO HOTAKA 2008-12-04 US disclosed
US-7374699-B2 Slurry rheology modifier KAO CORPORATION (JP) 2008-05-20 US disclosed
CN-1268573-C Slurry rheology modifier KAO CORP (JP) 2006-08-09 CN disclosed
US-20030200901-A1 Slurry rheology modifier KAO CORPORATION (JP) 2003-10-30 US disclosed
CN-1392111-A Slurry rheology modifier KAO CORP (JP) 2003-01-22 CN disclosed
EP-1266875-A2 Slurry rheology modifier Kao Corporation (JP) 2002-12-18 EP disclosed