SCHEMBL4974686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4974491	0.87	KDR (0.45)	METKDRPDPK1FLT3NTRK1
	SCHEMBL445790	0.85	KDR (0.55)	KDRFLT3CITMAP3K7RIPK2
	SCHEMBL187830	0.85	KDR (0.55)	KDRFLT3CITMAP3K7RIPK2
	SCHEMBL6013568	0.85	KDR (0.55)	KDRFLT3CITMAP3K7RIPK2
	SCHEMBL4977912	0.85	KDR (0.44)	METKDRPDPK1FLT3NTRK1
	SCHEMBL4975078	0.85	KDR (0.44)	METKDRPDPK1FLT3NTRK1
	SCHEMBL6106380	0.85	KDR (0.46)	KDRPDPK1FLT3CITMAP3K7
	SCHEMBL6104030	0.85	KDR (0.46)	KDRPDPK1FLT3CITMAP3K7
	SCHEMBL5012043	0.85	MEN1 (0.43)	METKDRPDPK1BRAFFLT1
	SCHEMBL4973509	0.85	MEN1 (0.43)	METKDRPDPK1BRAFFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.