SCHEMBL49748

SCHEMBL49748

F[Si](F)(F)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
ALDH1A1 P00352 5/20 0.35
TSHR P16473 5/20 0.33
TDP1 Q9NUW8 4/20 0.33
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
LMNA P02545 2/20 0.33
RAB9A P51151 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
IDO1 P14902 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGS2 P35354 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
NOTUM Q6P988 1/20 0.32
CA1 P00915 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705400 0.81 NR1H2 (0.32) NR1H2NR1H3
SCHEMBL701465 0.79 ESR1 (0.36) ESR1ESR2ALDH1A1TSHRTDP1
SCHEMBL704195 0.79 ESR1 (0.36) ESR1ESR2ALDH1A1TSHRTDP1
SCHEMBL703156 0.76 ESR1 (0.40) ESR1ESR2ALDH1A1TSHRTDP1
SCHEMBL705989 0.76 ESR1 (0.40) ESR1ESR2ALDH1A1TSHRTDP1
SCHEMBL16710468 0.76 ALDH1A1 (0.50) ALDH1A1TSHRTDP1LMNARAB9A
SCHEMBL16710487 0.76 ALDH1A1 (0.50) ALDH1A1TSHRTDP1LMNARAB9A
SCHEMBL707750 0.73 ESR1 (0.44) ESR1ESR2ALDH1A1TSHRNR1H2
SCHEMBL1538615 0.73 TSHR (0.35) ESR1ESR2ALDH1A1TSHRTDP1
SCHEMBL1538906 0.73 TSHR (0.35) ESR1ESR2ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724507-A1 SOLUTION CATALYST SYSTEMS AND USES THEREOF ExxonMobil Technology and Engineering Company (US) 2026-04-15 EP claimed
EP-4724505-A1 NON-COORDINATED ALKYLALUMINUM FREE ANION MODIFIED ALUMOXANES AND METHODS THEREOF ExxonMobil Technology and Engineering Company (US) 2026-04-15 EP claimed
US-20260094872-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES SEPION TECH INC (US) 2026-04-02 US claimed
EP-4595143-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES Sepion Technologies, Inc. (US) 2025-08-06 EP claimed
CN-120202571-A Ternary solvent electrolyte for high voltage and high rate lithium battery 赛鹏科技有限公司 2025-06-24 CN claimed
WO-2024253829-A1 SOLUTION CATALYST SYSTEMS AND USES THEREOF ExxonMobil Technology and Engineering Company (US) 2024-12-12 WO claimed
WO-2024253831-A1 NON-COORDINATED ALKYLALUMINUM FREE ANION MODIFIED ALUMOXANES AND METHODS THEREOF ExxonMobil Technology and Engineering Company (US) 2024-12-12 WO claimed
CN-117936910-A Lithium corrosion resistant electrolyte and preparation method and application thereof 浙江大学 2024-04-26 CN claimed
WO-2024073410-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES SEPION TECHNOLOGIES, INC. (US) 2024-04-04 WO claimed
US-11904352-B2 Low dielectric constant film and preparation method thereof JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2024-02-20 US claimed
US-6488414-B1 Optical fiber component with shaped optical element and method of making same CORNING INCORPORATED 2002-12-03 US claimed
CN-1341224-A Optical fiber component with shaped optical element and method of making same CORNING INC (US) 2002-03-20 CN claimed
EP-1157292-A1 OPTICAL FIBER COMPONENT WITH SHAPED OPTICAL ELEMENT AND METHOD OF MAKING SAME CORNING INCORPORATED (US) 2001-11-28 EP claimed
US-20010016093-A1 Athermalized integrated optical waveguide devices LUMENTUM OPTICS INC. 2001-08-23 US claimed
WO-2001051967-A1 ATHERMALIZED INTEGRATED OPTICAL WAVEGUIDE DEVICES CORNING INCORPORATED (US) 2001-07-19 WO claimed
EP-1116973-A1 Athermalized integrated optical waveguide devices Corning Incorporated (US) 2001-07-18 EP claimed
WO-2000046622-A1 OPTICAL FIBER COMPONENT WITH SHAPED OPTICAL ELEMENT AND METHOD OF MAKING SAME CORNING INCORPORATED (US) 2000-08-10 WO claimed
EP-0285092-B1 PROCESS TO STRENGTHEN THE ADHERENCE OF POLYMER MATERIALS Wacker-Chemie GmbH (DE) 1990-11-14 EP claimed
US-4874638-A PRECOATING AN ALKALINE CARBONATE SURFACE WITH AN APROTIC SOLVENT SOLUTION CONTAINING AN ORGANO SILICON FLUORIDE; DESOLVENTIZING WACKER-CHEMIE GMBH (DE) 1989-10-17 US claimed
US-4207266-A CARBON TETRALIDE, HYDROGEN FLUORIDE, LEWIS ACID AD AROMATIC HYDROCARBON ROHM AND HAAS COMPANY (US) 1980-06-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260094872-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES CACNA1C, TIMCC, SLC8A1 ESR1 871/4885ESR2 2160/4885ALDH1A1 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.