Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975013 | 1.00 | STS (0.32) | STSALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL4975005 | 1.00 | STS (0.32) | STSALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL3609639 | 0.90 | MMP13 (0.32) | ENPP3ENPP1ENPP2 | |
| SCHEMBL3609637 | 0.90 | MMP13 (0.32) | ENPP3ENPP1ENPP2 | |
| SCHEMBL3609636 | 0.90 | MMP13 (0.32) | ENPP3ENPP1ENPP2 | |
| SCHEMBL3609643 | 0.90 | MMP13 (0.32) | ENPP3ENPP1ENPP2 | |
| SCHEMBL3604811 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL3604810 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL3604807 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL4974681 | 0.86 | ABCG2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |