SCHEMBL4975017

SCHEMBL4975017

CC1OC1CCCC(=O)CCCCCCC(=O)CCCC1CCO1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694697 0.86 ALDH1A1 (0.43) EPHX1SMN1; SMN2ALDH1A1THRBMAPT
SCHEMBL7704502 0.71 ALDH1A1 (0.44) EPHX1SMN1; SMN2ALDH1A1THRBMAPT
SCHEMBL5193552 0.69 TSHR (0.50) ALDH1A1LMNAKMT2A
SCHEMBL30837971 0.68 ALDH1A1 (0.52) EPHX1TP53HPGDALOX12SMN1; SMN2
SCHEMBL7707317 0.68 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1THRB
SCHEMBL12677249 0.66 EPHX1 (0.76) EPHX1TP53HPGDALOX12ALDH1A1
SCHEMBL4223419 0.66 ALDH1A1 (0.54) EPHX1SMN1; SMN2ALDH1A1
SCHEMBL11349778 0.66 ALDH1A1 (0.48) EPHX1SMN1; SMN2ALDH1A1
SCHEMBL9258460 0.65 EPHX1 (0.55) EPHX1TP53HPGDALOX12SMN1; SMN2
SCHEMBL9686164 0.65 ALDH1A1 (0.70) EPHX1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187644-B2 Continuous processing of asphalt formulations BUILDING MATERIALS INVESTMENT CORPORATION (US) 2015-11-17 US disclosed
US-20140275337-A1 CONTINUOUS PROCESSING OF ASPHALT FORMULATIONS BUILDING MATERIALS INVESTMENT CORPORATION (US) 2014-09-18 US disclosed
EP-1285932-B1 Barium metal containing catalyst system GOODYEAR TIRE & RUBBER (US) 2008-09-24 EP disclosed
EP-1892125-A2 Amine containing catalyst system and methods of use thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-02-27 EP disclosed
US-7321017-B1 Amine containing catalyst system and methods of use thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-01-22 US disclosed
US-7291687-B1 Catalyst system for synthesizing rubbery polymers having a high trans microstructure content THE GOODYEAR TIRE AND RUBBER COMPANY (US) 2007-11-06 US disclosed
US-7285605-B1 Batch process for synthesizing rubbery polymers having a high trans microstructure content THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-10-23 US disclosed
US-7087549-B2 Calcium-based catalyst system THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-08-08 US disclosed
US-20050181935-A1 Calcium-based catalyst system THE GOODYEAR TIRE & RUBBER COMPANY 2005-08-18 US disclosed
EP-1191045-B1 Synthesis of styrene-isoprene rubber GOODYEAR TIRE & RUBBER (US) 2004-11-17 EP disclosed
US-5100965-A Process for synthesizing high trans polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-31 US disclosed
US-4845165-A ORGANOLITHIUM CATALYST; TIN TETRACHLORIDE BRANCHING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-07-04 US disclosed
EP-0282437-A2 Polymerization process THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-09-14 EP disclosed
EP-0258167-A2 Modifier for lithium catalysts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-02 EP disclosed
US-4696986-A 1,2,3- OR 1,2,4-TRIALKOXYBENZENE MODIFIERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-29 US disclosed
US-4647634-A Randomizers for use in solution polymerizations THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-03-03 US disclosed
US-4163764-A COUPLED ADDITION POLYMER PHILLIPS PETROLEUM COMPANY (US) 1979-08-07 US disclosed
US-4137391-A Continuous solution polymerization of a conjugated diene with a monovinylaromatic compound using alkoxysilicon treating agents in the first reactor means of a reactor series PHILLIPS PETROLEUM COMPANY (US) 1979-01-30 US disclosed
US-4107236-A OZONE-RESISTANT THERMOPLASTIC ELASTOMERS PHILLIPS PETROLEUM COMPANY (US) 1978-08-15 US disclosed
US-4091198-A Suppressing gel in the continuous solution polymerization of a conjugated diene with a monovinyl aromatic compound PHILLIPS PETROLEUM COMPANY (US) 1978-05-23 US disclosed