Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SCN4A | P35499 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882581 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1CYP2D6SCN4ALMNA | |
| SCHEMBL8012133 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1CYP2D6SCN4ALMNA | |
| SCHEMBL3466659 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1CYP2D6HCAR3HPGD | |
| SCHEMBL3466658 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1CYP2D6HCAR3HPGD | |
| SCHEMBL30776762 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1CYP2D6HCAR3HPGD | |
| SCHEMBL5794071 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1CYP2D6HCAR3HPGD | |
| SCHEMBL9058079 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1CYP2D6LMNACYP1A2 | |
| SCHEMBL11571832 | 0.81 | NLRP3 (0.38) | ALDH1A1CYP2D6SCN4ALMNASCN1A | |
| SCHEMBL13626615 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1CYP2D6HCAR3ATM | |
| SCHEMBL11227410 | 0.78 | MEN1 (0.44) | KDM4EALDH1A1CYP2D6SCN5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237844-A1 | PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES | Celgro (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001044162-A1 | PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES | CELGRO (US) | 2001-06-21 | — | — | WO | claimed |
| US-6107521-A | Process for the preparation of secondary amines | CELGRO (US) | 2000-08-22 | — | — | US | claimed |
| CN-111285770-B | Asymmetric reductive amination method based on fructose-derived chiral monodentate phosphite ligand ketone | 中国科学院大连化学物理研究所 | 2023-06-09 | — | — | CN | disclosed |
| CN-111285775-B | Method for applying fructose-derived pyridine alcohol chiral ligand to asymmetric reductive amination of ketone | 中国科学院大连化学物理研究所 | 2023-06-09 | — | — | CN | disclosed |
| CN-110551033-B | Method for preparing chiral amine through asymmetric reductive amination of ketone | 中国科学院大连化学物理研究所 | 2022-04-12 | — | — | CN | disclosed |
| CN-110551032-B | Asymmetric reductive amination method for catalyzing ketone by iridium chiral phosphine-aminophosphine ligand system | 中国科学院大连化学物理研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-110551034-B | Asymmetric reductive amination method of ketone | 中国科学院大连化学物理研究所 | 2021-11-09 | — | — | CN | disclosed |
| CN-111285773-A | Method for preparing chiral amine based on glucose-derived monodentate phosphite ligand asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2020-06-16 | — | — | CN | disclosed |
| CN-111285775-A | Method for applying fructose-derived pyridinol chiral ligand to asymmetric reductive amination of ketone | 中国科学院大连化学物理研究所 | 2020-06-16 | — | — | CN | disclosed |
| CN-111285770-A | Asymmetric reductive amination method based on fructose derived chiral monodentate phosphite ligand ketone | 中国科学院大连化学物理研究所 | 2020-06-16 | — | — | CN | disclosed |
| US-5371256-A | With rhodium and iridium | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0564406-A1 | Ferrocenyldiphosphine as ligands for homogeneous catalysts | CIBA-GEIGY AG (CH) | 1993-10-06 | — | — | EP | disclosed |
| US-5112999-A | With diphosphines and diphosphinites, catalysts for hydrogenation of imines to secondary amines | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0419409-A2 | Iridium complexes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |
| US-4264520-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| US-4219493-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1980-08-26 | — | — | US | disclosed |
| US-4151295-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-4019894-A | 2-CHLORO-2',6'-DIMETHYL-N-(1-METHOXYPROP-2-YL)ACETANILIDE; HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |
| US-3952056-A | 2-CHLORO-2',6'-DIMETHYL-N-(1-METHOXYPROP-2-YL)-ACETANILIDE | CIBA-GEIGY CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |