Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455516 | 0.84 | MAPT (0.39) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4975574 | 0.79 | MAPT (0.44) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4975567 | 0.74 | MAPT (0.47) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1455233 | 0.72 | MAPT (0.51) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1454546 | 0.72 | TP53 (0.49) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4976907 | 0.71 | MAPT (0.51) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1454100 | 0.71 | MAPT (0.47) | MAPTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL2971539 | 0.70 | HDAC1 (0.53) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1455205 | 0.69 | MAPT (0.46) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4976896 | 0.68 | MAPT (0.52) | MAPTHPGDALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |