Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976907 | 0.88 | MAPT (0.51) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL1455785 | 0.85 | MAPT (0.39) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL4986213 | 0.85 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL4975567 | 0.79 | MAPT (0.47) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL4975659 | 0.79 | MAPT (0.43) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL1454864 | 0.75 | MAPT (0.46) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL4976624 | 0.73 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2971539 | 0.73 | HDAC1 (0.53) | MAPTALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL1454126 | 0.72 | MAPT (0.47) | MAPTALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL4976896 | 0.71 | MAPT (0.52) | MAPTALDH1A1HPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |