Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975567 | 0.89 | MAPT (0.47) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1454861 | 0.85 | MAPT (0.46) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4976616 | 0.83 | MEN1 (0.53) | MAPTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL4976907 | 0.79 | MAPT (0.51) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4973595 | 0.77 | RAB9A (0.50) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1455784 | 0.76 | MAPT (0.41) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL11957597 | 0.75 | HDAC2 (0.52) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1455121 | 0.74 | MAPT (0.57) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL4982491 | 0.74 | KDM4E (0.54) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1455605 | 0.73 | DEGS1 (0.50) | MAPTHPGDALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |