SCHEMBL4976102

SCHEMBL4976102

C=C(CN)C(=O)N(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP8 P22894 1/20 0.34
ALDH1A1 P00352 2/20 0.32
ALDH2 P05091 2/20 0.32
KMT2A Q03164 2/20 0.32
PHGDH O43175 1/20 0.32
PLIN1 O60240 1/20 0.32
GMNN O75496 1/20 0.32
TRPA1 O75762 1/20 0.32
ABCB11 O95342 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP3A4 P08684 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
FBP1 P09467 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2503822 0.82 LMNA (0.38) LMNAMMP1MMP2MMP3MMP8
SCHEMBL4978433 0.82 CA12 (0.41) ALDH1A1TP53HPGDTSHRCA12
SCHEMBL11523442 0.80 LMNA (0.39) LMNAMMP1MMP2MMP3MMP8
SCHEMBL18744476 0.79
SCHEMBL1042979 0.79 LMNA (0.40) LMNAMMP1MMP2MMP3MMP8
SCHEMBL4974659 0.79 CA12 (0.45) MMP1MMP2MMP3MMP8ALDH1A1
SCHEMBL19359715 0.78 LMNA (0.37) LMNAMMP1MMP2MMP3MMP8
SCHEMBL2505688 0.77 BLM (0.43) LMNAALDH1A1ALDH2KMT2ACYP1A2
SCHEMBL1629859 0.76 LMNA (0.41) LMNAMMP1MMP2MMP3MMP8
SCHEMBL11243264 0.76 LMNA (0.52) LMNAMMP1MMP2MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435418-B1 A dispersant/antioxidant viscosity index improving lubricant additive TEXACO DEVELOPMENT CORP (US) 1995-01-04 EP claimed
US-4666617-A ALKYLAMINO-ACRYLATE POLYMERS, FATTY ACID, ALKYL PHOSPHATES NIPPON KOKAN KABUSHIKI KAISHA (JP) 1987-05-19 US claimed
EP-2818505-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-02-01 EP disclosed
EP-2787033-B1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-9340663-B2 Rubber composition for tire, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-05-17 US disclosed
EP-2644664-B1 Actinic radiation-curing type ink composition, inkjet recording method, decorative sheet, decorative sheet molded product, process for producing in-mold molded article, and in-mold molded article FUJIFILM CORP (JP) 2015-07-29 EP disclosed
US-8940813-B2 Actinic radiation-curing type ink composition, inkjet recording method, decorative sheet, decorative sheet molded product, process for producing in-mold molded article, and in-mold molded article FUJIFILM CORPORATION (JP) 2015-01-27 US disclosed
EP-2818505-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-12-31 EP disclosed
US-20140371372-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-12-18 US disclosed
US-20140323660-A1 RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-30 US disclosed
US-8865836-B2 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
EP-2787033-A1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2014-10-08 EP disclosed
US-20130260092-A1 ACTINIC RADIATION-CURING TYPE INK COMPOSITION, INKJET RECORDING METHOD, DECORATIVE SHEET, DECORATIVE SHEET MOLDED PRODUCT, PROCESS FOR PRODUCING IN-MOLD MOLDED ARTICLE, AND IN-MOLD MOLDED ARTICLE FUJIFILM CORPORATION (JP) 2013-10-03 US disclosed
EP-2644664-A1 Actinic radiation-curing type ink composition, inkjet recording method, decorative sheet, decorative sheet molded product, process for producing in-mold molded article, and in-mold molded article Fujifilm Corporation (JP) 2013-10-02 EP disclosed
EP-2543702-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2013-09-11 EP disclosed
US-20130012660-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-10 US disclosed
EP-2543702-A1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2013-01-09 EP disclosed
US-7339005-B2 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-04 US disclosed
US-20040152845-A1 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-08-05 US disclosed
US-4761358-A Electrostatographic encapsulated toner FUJI PHOTO FILM CO., LTD. (JP) 1988-08-02 US disclosed