Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL219475 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL5422753 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL5144360 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL10602050 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL162701 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL29202857 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL10479108 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2127923 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL8723716 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL5583382 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422522-B1 | Column packing and process for production thereof | SHISEIDO CO LTD (JP) | 2013-10-30 | — | — | EP | disclosed |
| US-7329386-B2 | Column packing material and method for producing the same | SHISEIDO CO., LTD. (JP) | 2008-02-12 | — | — | US | disclosed |
| EP-1422522-A1 | COLUMN PACKING AND PROCESS FOR PRODUCTION THEREOF | Shiseido Co., Ltd. (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-20040043493-A1 | Column packing material and method for production thereof | SANYO FINE IRICA TECHNOLOGY CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| US-5527617-A | IMPROVED WEATHER RESISTANCE, ABRASION RESISTANCE AND SLIDING PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0684291-A1 | Mica group pigment-containing water-based coating composition | Nippon Paint Co., Ltd. (JP) | 1995-11-29 | — | — | EP | disclosed |