Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965576 | 0.95 | KMT2A (0.49) | KMT2AALDH1A1HTTCA1CA2 | |
| SCHEMBL4965413 | 0.94 | KMT2A (0.47) | KMT2AALDH1A1HTTCA1CA2 | |
| SCHEMBL14178044 | 0.86 | CA2 (0.53) | KMT2AALDH1A1HTTCA1CA2 | |
| SCHEMBL28623815 | 0.83 | CA2 (0.58) | KMT2ACA1CA2CA12CA9 | |
| SCHEMBL14177864 | 0.81 | CA12 (0.44) | KMT2AALDH1A1HTTCA1CA2 | |
| SCHEMBL14177861 | 0.80 | CA2 (0.43) | KMT2AALDH1A1HTTCA1CA2 | |
| SCHEMBL4981144 | 0.80 | CA12 (0.66) | KMT2AALDH1A1HTTCA1CA2 | |
| SCHEMBL28112129 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTCA1CA2CA12 | |
| SCHEMBL4967425 | 0.79 | CA12 (0.68) | KMT2ACA1CA2CA12CA9 | |
| SCHEMBL14177869 | 0.79 | CA2 (0.44) | KMT2AALDH1A1HTTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071421-A1 | NITRATE ESTERS OF CARBONIC ANHYDRASE INHIBITORS | NICOX S.A. (FR) | 2008-06-19 | — | — | WO | disclosed |