⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494209 | 0.80 | AKR1B1 (0.35) | — | |
| SCHEMBL329387 | 0.78 | — | — | |
| SCHEMBL1258957 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3710347 | 0.76 | CA2 (0.39) | — | |
| SCHEMBL440583 | 0.76 | — | — | |
| SCHEMBL21670717 | 0.76 | CA2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL28129331 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL29492947 | 0.74 | DUSP3 (0.34) | — | |
| SCHEMBL28399588 | 0.73 | AKR1B1 (0.31) | — | |
| SCHEMBL21962469 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438298-A | N- hydroxysulfonamide amine derivative as the nitryl oxygroup donor for thering is physiology to be worth | 约翰斯霍普金斯大学 | 2019-03-08 | — | — | CN | claimed |
| JP-62263159-A | — | — | None | — | — | JP | disclosed |
| JP-10212277-A | — | — | None | — | — | JP | disclosed |
| EP-4577536-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | Hotspot Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| US-20250161281-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| US-20250145620-A1 | METHODS OF PREPARING HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS INCORPORATED | 2025-05-08 | — | — | US | disclosed |
| US-12234245-B2 | Sulfonimidamide compounds as inhibitors of interleukin-1 activity | GENENTECH, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| US-12152028-B2 | Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS INCORPORATED (US) | 2024-11-26 | — | — | US | disclosed |
| EP-4031547-B1 | PLASMA KALLIKREIN INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-17 | — | — | EP | disclosed |
| EP-0613896-A1 | Process for the preparation of sulfonylurea derivatives and intermediates for this process | LUCKY LTD. (KR) | 1994-09-07 | — | — | EP | disclosed |
| EP-0318602-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| EP-0530616-A1 | Pyrazolylsulfonylguanidino pyrimidines as herbicides | BAYER AG (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0224842-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4881965-A | CONTROLLING WILD OATS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| US-4844728-A | Pyrazolesulfonamide derivative, and herbicide containing it | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0318602-A1 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| JP-S62263159-A | PYRAZOLE DERIVATIVE AND PRODUCTION THEREOF | NISSAN CHEM IND LTD | 1987-11-16 | — | — | JP | disclosed |
| EP-0224842-A2 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |
| EP-0189069-A2 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |