Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970042 | 0.86 | IDO1 (0.53) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28072858 | 0.78 | TSHR (0.46) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL776890 | 0.75 | TSHR (0.48) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL775058 | 0.75 | TSHR (0.48) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9955937 | 0.74 | TDP1 (0.58) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3956655 | 0.73 | TSHR (0.46) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8534439 | 0.72 | DPP4 (0.43) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22115704 | 0.72 | TAAR1 (0.46) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Fluoride SCHEMBL28760653 | 0.72 | TDP1 (0.56) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23713651 | 0.71 | TSHR (0.44) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345188-B2 | Process for preparing benzhydrylthioacetamide | MALLINCKRODT INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-20080027240-A1 | Process for Preparing Benzhydrylthioacetamide | MALLINCKRODT US POOL LLC | 2008-01-31 | — | — | US | disclosed |
| EP-1678129-A1 | IMPROVED PROCESS FOR PREPARING BENZHYDRYLTHIOACETAMIDE | MALLINCKRODT INC. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042479-A1 | IMPROVED PROCESS FOR PREPARING BENZHYDRYLTHIOACETAMIDE | MALLINCKRODT INC. (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027240-A1 | Process for Preparing Benzhydrylthioacetamide | ABAT, NUDT1, OTC | TSHR 120/4885CYP1A2 631/4885CYP3A4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.