Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22067721 | 0.86 | MAPK8 (0.39) | MAPK8PARP1TAAR1RAB9ANPC1 | |
| SCHEMBL21356997 | 0.86 | TAAR1 (0.56) | MAPK8PARP1TAAR1MEN1KMT2A | |
| SCHEMBL4638489 | 0.85 | PARP1 (0.46) | MAPK8PARP1TAAR1RAB9ANPC1 | |
| SCHEMBL6022904 | 0.84 | TAAR1 (0.42) | MAPK8PARP1TAAR1RAB9ANPC1 | |
| SCHEMBL29140046 | 0.84 | CSNK2A1 (0.48) | CSNK2A1HDAC7MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4604668 | 0.83 | PARP1 (0.42) | MAPK8PARP1TAAR1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL5614036 | 0.81 | PARP1 (0.41) | MAPK8PARP1TAAR1RAB9ANPC1 | |
| SCHEMBL9838573 | 0.81 | HSP90AB1 (0.43) | TAAR1RAB9ANPC1CSNK2A1HDAC7 | |
| SCHEMBL15676699 | 0.80 | RAB9A (0.48) | RAB9ANPC1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28431089 | 0.80 | MAPT (0.40) | SIRT1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987022-A1 | PYRIDINONE PYRAZOLE UREA AND PYRIMIDINONE PYRAZOLE UREA DERIVATIVES | Pfizer Products Inc. (US) | 2008-11-05 | — | — | EP | claimed |
| WO-2007091176-A1 | PYRIDINONE PYRAZOLE UREA AND PYRIMIDINONE PYRAZOLE UREA DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | claimed |