SCHEMBL4976834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4973863	0.97	KDR (0.59)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL5424280	0.92	KDR (0.57)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL4974477	0.91	KDR (0.69)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL5009499	0.91	KDR (0.68)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL4976511	0.88	KDR (0.55)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL4973327	0.87	KDR (0.61)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL11986954	0.86	KDR (0.55)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL5421728	0.86	KDR (0.57)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL4975633	0.85	JAK1 (0.45)	KDRRETMAP3K20RIPK3FLT3
	SCHEMBL4968522	0.85	KDR (0.58)	KDRRETMAP3K20RIPK3FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.