SCHEMBL497684

SCHEMBL497684

CC1=Cc2c(cccc2-c2ccccc2)C1=[Zr](Cl)(Cl)(Cl)(Cl)(=C1C(C)=Cc2c1cccc2-c1ccccc1)=[Si](C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5084803 0.71 CD274 (0.42) PDCD1CD274CYP2A6
Hydrochloric Acid SCHEMBL497685 0.70 PDCD1 (0.32) PDCD1CD274CYP2A6
SCHEMBL27724373 0.69 ALDH1A1 (0.52) PDCD1CD274
SCHEMBL4623134 0.68 PDCD1 (0.42) PDCD1CD274CYP2A6
SCHEMBL25785668 0.60 PDCD1 (0.64) PDCD1CD274CYP2A6
SCHEMBL1827132 0.59 PDCD1 (0.39) PDCD1CD274CYP2A6
SCHEMBL60836 0.59 PDCD1 (0.39) PDCD1CD274CYP2A6
SCHEMBL2048988 0.58 ALDH1A1 (0.46) PDCD1CD274CYP2A6
SCHEMBL7643421 0.58 PDCD1 (0.38) PDCD1CD274CYP2A6
SCHEMBL20548534 0.58 PDCD1 (0.38) PDCD1CD274CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150126672-A1 USE OF THERMOPLASTIC COMPOSITION COMPRISING POLYETHER-BLOCK COPOLYAMIDES AS ADDITIVE TOTAL RES & TECHNOLOGY FELUY (BE) 2015-05-07 US disclosed
US-8961856-B2 Use of thermoplastic composition comprising polyether-block copolyamides as additive TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2015-02-24 US disclosed
US-8703854-B2 Use of polyetheresters for rotomolding TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2014-04-22 US disclosed
US-20130093118-A1 USE OF THERMOPLASTIC COMPOSITION COMPRISING POLYETHER-BLOCK COPOLYAMIDES AS ADDITIVE TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-04-18 US disclosed
US-20130049262-A1 Use of Fluoropolymers for Rotomolding TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-02-28 US disclosed
US-8372329-B1 Use of thermoplastic composition comprising polyether-block copolyamides as additive TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-02-12 US disclosed
US-8182733-B2 Use of thermoplastic composing polyethlene glycol as additive TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2012-05-22 US disclosed
US-8105525-B2 As densification aid; improving polyethylene processability; reducing numer of air bubbles; impact strength TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2012-01-31 US disclosed
US-20110313096-A1 Use of Polyetheresters for Rotomolding TOTAL PETROCHEMICALS RESEARCH FELUY 2011-12-22 US disclosed
US-20110127695-A1 Use of thermoplastic composition comprising thermoplastic polyurethanes as additive TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-06-02 US disclosed
EP-1751227-A1 USE OF POLYETHERESTERS FOR ROTOMOLDING TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-02-14 EP disclosed
EP-1749058-A1 USE OF THERMOPLASTIC COMPOSITION COMPRISING POLYETHER-BLOCK COPOLYAMIDES AS ADDITIVE TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-02-07 EP disclosed
WO-2005118711-A1 USE OF THERMOPLASTIC COMPOSITION COMPRISING THERMOPLASTIC POLYURETHANES AS ADDITIVE TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-12-15 WO disclosed
WO-2005118709-A1 USE OF POLYETHERESTERS FOR ROTOMOLDING TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-12-15 WO disclosed
WO-2005118708-A1 USE OF THERMOPLASTIC COMPOSITION COMPRISING POLYETHER-BLOCK COPOLYAMIDES AS ADDITIVE TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-12-15 WO disclosed
EP-1600478-A1 Use of thermoplastic composition comprising thermoplastic polyurethanes as additive TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-11-30 EP disclosed
EP-1600475-A1 Use of Thermoplastic Composition Comprising Polyether-Block Copolyamides as Additive TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-11-30 EP disclosed
EP-1600477-A1 Use of thermoplastic composition comprising polyethylene glycol as additive TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-11-30 EP disclosed
EP-1600476-A1 Use of polyetheresters for rotomolding TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-11-30 EP disclosed
EP-1600474-A1 Use of fluoropolymers for rotomolding TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-11-30 EP disclosed