SCHEMBL4976876

SCHEMBL4976876

Nc1ccc(OS(N)(=O)=O)cc1

nearest known ligand 0.80

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 15/20 0.80
CA9 Q16790 15/20 0.80
CA1 P00915 14/20 0.64
STS P08842 5/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4666147 0.93 CA2 (0.70) CA2CA9CA1STS
SCHEMBL4084109 0.82 CA2 (0.52) CA2CA9CA1STS
SCHEMBL3380638 0.78 TSHR (0.50) CA2CA9CA1STS
SCHEMBL6037 0.78 CA2 (0.48) CA2CA9CA1
SCHEMBL2236572 0.78 CA2 (1.00) CA2CA9CA1STS
SCHEMBL9451471 0.78 CA2 (1.00) CA2CA9CA1STS
SCHEMBL9451266 0.78 CA2 (0.76) CA2CA9CA1STS
SCHEMBL9451347 0.78 CA2 (1.00) CA2CA9CA1STS
SCHEMBL9451224 0.78 CA2 (0.76) CA2CA9CA1STS
SCHEMBL17129828 0.78 CA2 (0.48) CA2CA9CA1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504808-A Compound, preparation method and application thereof 四川科伦药物研究院有限公司 2025-02-25 CN disclosed
CN-104203773-A Aerosol product and method for manufacturing same DAIZO CORP 2014-12-10 CN disclosed
CN-102166163-B Hair treatment agent composition and method for production thereof NONOGAWA SHOJI LTD. (JP) 2014-10-29 CN disclosed
CN-102307559-B Hair dye composition, oxidation hair dye composition and method for prevention of change in color tone of hair dyeing HOYU KK 2014-02-26 CN disclosed
CN-102307559-A Hair dye composition, oxidation hair dye composition and method for prevention of change in color tone of hair dyeing HOYU KK 2012-01-04 CN disclosed
CN-102166163-A Hair treatment agent composition and method for production thereof NONOGAWA SHOJI LTD 2011-08-31 CN disclosed
US-7338959-B2 Diamino-pyrimidines and their use as angiogenesis inhibitors SMITHKLINE BEECHAM CORPORATION (US) 2008-03-04 US disclosed
EP-1487824-B1 DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORP (US) 2007-06-20 EP disclosed
US-20050234083-A1 Diamino-pyrimidines and their use as angiogenesis inhibitors SMITHKLINE BEECHAM CORPORATION 2005-10-20 US disclosed
CN-1599590-A Hair treatment agent composition and method for producing same NONOGAWA SHOJI LTD (JP) 2005-03-23 CN disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4039529-A Cycloaliphatic dicarbonyl containing azo dyestuffs CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4014864-A POLYESTER FIBERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-4010150-A Red copper complexes of disazo compounds containing triazine groups NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-03-01 US disclosed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed
US-3954398-A Polyester fibers dyed with a disazo disperse dyestuff CIBA-GEIGY AG (CH) 1976-05-04 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3933786-A Heterocyclic-azo-phenyl compounds containing a styrl group CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234083-A1 Diamino-pyrimidines and their use as angiogenesis inhibitors TIE1, TEK, KDR CA2 3739/4885CA9 4248/4885CA1 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.