Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455260 | 0.85 | PTGS1 (0.48) | PTGS1DEGS1TRPV1NPC1RAB9A | |
| SCHEMBL4975269 | 0.77 | GCK (0.47) | NPC1RAB9AKCNQ3KCNQ2KDM4E | |
| SCHEMBL1455151 | 0.74 | MAPT (0.45) | NPC1RAB9AKCNQ3KCNQ2KDM4E | |
| SCHEMBL1453591 | 0.74 | KCNQ3 (0.47) | KCNQ3KCNQ2KDM4EALDH1A1LMNA | |
| SCHEMBL1455071 | 0.74 | PTGS1 (0.53) | PTGS1DEGS1TRPV1NPC1RAB9A | |
| SCHEMBL1453998 | 0.74 | NPC1 (0.54) | DEGS1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1454853 | 0.72 | MAPT (0.45) | PTGS1DEGS1PTGESHIF1AEPAS1 | |
| SCHEMBL1455664 | 0.72 | NPC1 (0.43) | NPC1RAB9AKCNQ3KCNQ2KDM4E | |
| SCHEMBL4973595 | 0.72 | RAB9A (0.50) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL4975567 | 0.72 | MAPT (0.47) | NPC1RAB9AKCNQ3KCNQ2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |