Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982491 | 0.88 | KDM4E (0.54) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1454615 | 0.85 | KDM4E (0.43) | RAB9ANPC1SMN1; SMN2TP53TDP1 | |
| SCHEMBL4985967 | 0.84 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2TP53TDP1 | |
| SCHEMBL4975269 | 0.78 | GCK (0.47) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4976896 | 0.77 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL4975567 | 0.77 | MAPT (0.47) | RAB9ANPC1SMN1; SMN2TP53TDP1 | |
| SCHEMBL1455533 | 0.74 | KDM4E (0.47) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL11957597 | 0.73 | HDAC2 (0.52) | RAB9ANPC1TDP1MAPTALDH1A1 | |
| SCHEMBL4977002 | 0.72 | PTGS1 (0.56) | RAB9ANPC1MAPTALDH1A1ALOX15 | |
| SCHEMBL1455605 | 0.72 | DEGS1 (0.50) | RAB9ANPC1TP53TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |