Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763555 | 0.73 | ATM (0.46) | ALDH1A1KMT2AHSD17B10GAALMNA | |
| SCHEMBL3117207 | 0.63 | ALDH1A1 (0.60) | ALDH1A1KMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL14228469 | 0.62 | KMT2A (0.37) | ALDH1A1IDO1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL20771373 | 0.61 | NPC1 (0.48) | ALDH1A1KMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL725810 | 0.60 | ALDH1A1 (0.75) | ALDH1A1KMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4088965 | 0.60 | CYP1A2 (0.62) | ALDH1A1KMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31105801 | 0.59 | KDM4E (0.47) | ALDH1A1KMT2ASMN1; SMN2TP53MAPT | |
| SCHEMBL526255 | 0.59 | GAA (0.67) | ALDH1A1IDO1KMT2AGAAMAPT | |
| SCHEMBL29838484 | 0.59 | GAA (0.67) | ALDH1A1IDO1KMT2AGAAMAPT | |
| SCHEMBL3482954 | 0.58 | NT5E (0.44) | ALDH1A1KMT2ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113975-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-05-15 | — | — | US | disclosed |
| US-20080096875-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096875-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, ETV6 | ALDH1A1 820/4885IDO1 2383/4885KMT2A 1846/4885 |
| US-20080113975-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, EIF2AK2 | ALDH1A1 500/4885IDO1 1748/4885KMT2A 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.