Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | IDO1 | P14902 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838484 | 1.00 | GAA (0.67) | GAAMAPTALDH1A1IDO1GLA | |
| SCHEMBL8296719 | 0.83 | IDO1 (0.61) | GAAMAPTALDH1A1IDO1GLA | |
| SCHEMBL4555003 | 0.83 | IDO1 (0.78) | GAAMAPTALDH1A1IDO1EPHX1 | |
| SCHEMBL3299680 | 0.82 | KMT2A (0.73) | GAAMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL68180 | 0.82 | MAPT (0.70) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10592427 | 0.82 | CYP1A2 (0.53) | GAAMAPTALDH1A1IDO1GLA | |
| SCHEMBL7308178 | 0.81 | IDO1 (0.63) | GAAMAPTALDH1A1IDO1GLA | |
| SCHEMBL238488 | 0.80 | GAA (1.00) | GAAMAPTALDH1A1IDO1GLA | |
| SCHEMBL5988806 | 0.80 | IDO1 (1.00) | GAAMAPTALDH1A1IDO1EPHX1 | |
| SCHEMBL29352610 | 0.79 | EPHX1 (0.70) | GAAMAPTALDH1A1IDO1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462459-B | Low-sensitization epoxy resin curing agent and preparation method thereof | 安徽美东生物材料有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-116024136-B | Burkholderia vietnamensis and application thereof in treatment of dye wastewater containing 3, 4-dichlorophenyl thiourea | 常州大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119462459-A | Low-sensitization epoxy resin curing agent and preparation method thereof | 安徽美东生物材料有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-115448863-B | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115466177-B | Method for preparing 1, 4-diacetoxy-2-butene | 中国科学院大连化学物理研究所 | 2024-02-02 | — | — | CN | claimed |
| CN-116024136-A | Burkholderia vietnamensis and application thereof in treatment of dye wastewater containing 3, 4-dichlorophenyl thiourea | 常州大学 | 2023-04-28 | — | — | CN | claimed |
| CN-114432901-B | Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| WO-2022257025-A1 | MONATOMICALLY DISPERSED PALLADIUM-BASED CATALYST, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国科学院大连化学物理研究所 | 2022-12-15 | — | — | WO | claimed |
| CN-115466177-A | Method for preparing 1, 4-diacetyloxy-2-butene | 中国科学院大连化学物理研究所 | 2022-12-13 | — | — | CN | claimed |
| CN-115445636-A | Monoatomic dispersed palladium-based catalyst, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-12-09 | — | — | CN | claimed |
| CN-115448863-A | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2022-12-09 | — | — | CN | claimed |
| WO-2022105199-A1 | PALLADIUM-BASED CATALYST, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院大连化学物理研究所 | 2022-05-27 | — | — | WO | claimed |
| CN-114432901-A | Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-105503678-A | Clean production method of 1-(3,4-dichlorophenyl)-2-thiourea | JIANGSU YUANZHENG CHEMICAL CO LTD | 2016-04-20 | — | — | CN | claimed |
| US-7897720-B2 | Method for removing catalyst residues from polymer solution and polymers purified by the method | LG CHEM, LTD. (KR) | 2011-03-01 | — | — | US | claimed |
| US-20100029900-A1 | METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD | LG CHEM, LTD. (KR) | 2010-02-04 | — | — | US | claimed |
| WO-2008056938-A1 | METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD | LG CHEM, LTD. (KR) | 2008-05-15 | — | — | WO | claimed |
| EP-1339668-A2 | BISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIRUS | GUILFORD PHARMACEUTICALS INC. (US) | 2003-09-03 | — | — | EP | claimed |
| WO-2002044126-A2 | BISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIRUS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-06-06 | — | — | WO | claimed |
| CN-119462459-B | Low-sensitization epoxy resin curing agent and preparation method thereof | 安徽美东生物材料有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-116024136-B | Burkholderia vietnamensis and application thereof in treatment of dye wastewater containing 3, 4-dichlorophenyl thiourea | 常州大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-116024136-B | Burkholderia vietnamensis and application thereof in treatment of dye wastewater containing 3, 4-dichlorophenyl thiourea | 常州大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-119462459-A | Low-sensitization epoxy resin curing agent and preparation method thereof | 安徽美东生物材料有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-11-28 | — | — | US | disclosed |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-05-07 | — | — | US | disclosed |
| CN-115448863-B | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115448863-B | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115448863-B | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115466177-B | Method for preparing 1, 4-diacetoxy-2-butene | 中国科学院大连化学物理研究所 | 2024-02-02 | — | — | CN | disclosed |
| CN-115445636-B | Monoatomic dispersed palladium-based catalyst and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-12-12 | — | — | CN | disclosed |
| US-20230263167-A1 | METHOD OF PREPARING A BISMUTH SULFIDE PARTICLE CONTAINING ANTIBACTERIAL COMPOSITION | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-08-24 | — | — | US | disclosed |
| US-11700855-B2 | Method for preventing or reducing growth of a microorganism on a surface | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-07-18 | — | — | US | disclosed |
| CN-116024136-A | Burkholderia vietnamensis and application thereof in treatment of dye wastewater containing 3, 4-dichlorophenyl thiourea | 常州大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-116024136-A | Burkholderia vietnamensis and application thereof in treatment of dye wastewater containing 3, 4-dichlorophenyl thiourea | 常州大学 | 2023-04-28 | — | — | CN | disclosed |
| US-20230129765-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | DAICEL CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| CN-114432901-B | Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115611745-A | Method for continuously producing 3, 4-dichloronitrobenzene | 浙江闰土股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| EP-4108705-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | Daicel Corporation (JP) | 2022-12-28 | — | — | EP | disclosed |
| WO-2022257025-A1 | MONATOMICALLY DISPERSED PALLADIUM-BASED CATALYST, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国科学院大连化学物理研究所 | 2022-12-15 | — | — | WO | disclosed |
| CN-115466177-A | Method for preparing 1, 4-diacetyloxy-2-butene | 中国科学院大连化学物理研究所 | 2022-12-13 | — | — | CN | disclosed |
| CN-115445636-A | Monoatomic dispersed palladium-based catalyst, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-12-09 | — | — | CN | disclosed |
| CN-115448863-A | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115448863-A | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115448863-A | Continuous preparation process of 3, 4-dichlorophenyl thiourea | 浙江迪邦化工有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115135697-A | Process for producing polythioether compound | 株式会社大赛璐 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022105199-A1 | PALLADIUM-BASED CATALYST, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院大连化学物理研究所 | 2022-05-27 | — | — | WO | disclosed |
| CN-114432901-A | Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-113278149-A | Process for producing polythioether compound | 株式会社大赛璐 | 2021-08-20 | — | — | CN | disclosed |
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2021-07-08 | — | — | US | disclosed |
| CN-106748810-B | Treatment method of disperse dye intermediate | 浙江闰土研究院有限公司 | 2021-04-27 | — | — | CN | disclosed |
| US-20210061670-A1 | METHOD FOR PREVENTING OR REDUCING GROWTH OF A MICROORGANISM ON A SURFACE | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2021-03-04 | — | — | US | disclosed |
| US-10934176-B2 | Methods of degrading organic pollutants and preventing or treating microbe using Bi2S3-CdS particles | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2021-03-02 | — | — | US | disclosed |
| US-20200102228-A1 | METHODS OF DEGRADING ORGANIC POLLUTANTS AND PREVENTING OR TREATING MICROBE USING Bi2S3-CdS PARTICLES | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2020-04-02 | — | — | US | disclosed |
| CN-107098895-B | Benzoylaminothiazolylmethyl quinolinone derivative and preparation method and application thereof | 湖南大学 | 2020-01-07 | — | — | CN | disclosed |
| US-10385069-B2 | Imidazo[2,1-B]thiazole and 5,6-dihydroimidazo[2,1-B]thiazole derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB (SE) | 2019-08-20 | — | — | US | disclosed |
| CN-109971202-A | A kind of benzothiazoles dispersion dyes monomer compound and its synthetic method and application | 浙江迪邦化工有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109651157-A | The method for being nitrified using o-dichlorohenzene, hydrogen being added to prepare 3,4- dichloroaniline | 杨向党 | 2019-04-19 | — | — | CN | disclosed |
| US-10105687-B1 | Heterostructured Bi2S3—ZnS photocatalysts and methods thereof | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2018-10-23 | — | — | US | disclosed |
| US-20180282348-A1 | IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2018-10-04 | — | — | US | disclosed |
| CN-107973720-A | A kind of method of micro passage reaction synthesis 3,4- dichloroanilines | 黑龙江鑫创生物科技开发有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-107466296-A | Imidazo [2,1 b] thiazole and 5,6 glyoxalidine as S100 inhibitor simultaneously [2,1 b] thiazole | 活跃生物技术有限公司 | 2017-12-12 | — | — | CN | disclosed |
| WO-2017143230-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-24 | — | — | WO | disclosed |
| EP-2700636-B1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | ASAHI CHEMICAL IND (JP) | 2017-08-02 | — | — | EP | disclosed |
| CN-104059060-B | A kind of ketones derivant of 5 (methylene of 1H indoles 3) 1,3 thiazolidine 4 and its synthetic method and application | 西安交通大学 | 2017-08-01 | — | — | CN | disclosed |
| CN-106748810-A | A kind of processing method of disperse dyes intermediate | 浙江闰土研究院有限公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-2760856-B1 | SELECTIVE NR2B ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2016-09-14 | — | — | EP | disclosed |
| US-9359324-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-06-07 | — | — | US | disclosed |
| CN-103476764-B | Process for producing episulfide compound | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2016-05-25 | — | — | CN | disclosed |
| CN-105503678-A | Clean production method of 1-(3,4-dichlorophenyl)-2-thiourea | JIANGSU YUANZHENG CHEMICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503678-A | Clean production method of 1-(3,4-dichlorophenyl)-2-thiourea | JIANGSU YUANZHENG CHEMICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503678-A | Clean production method of 1-(3,4-dichlorophenyl)-2-thiourea | JIANGSU YUANZHENG CHEMICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| WO-2016042172-A1 | IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2016-03-24 | — | — | WO | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-16 | — | — | US | disclosed |
| US-9051293-B2 | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-09 | — | — | US | disclosed |
| CN-104610222-A | Process for preparing episulfide compounds | ASAHI KASEI CHEMICALS CORP | 2015-05-13 | — | — | CN | disclosed |
| CN-104059060-A | 5-(1H-indolyl-3-methylene)-1,3-thiazolidinyl-4-one derivatives, and synthesis method and application thereof | UNIV XI AN JIAOTONG | 2014-09-24 | — | — | CN | disclosed |
| CN-102603726-B | 5-(2-aminothiazole-4-yl) benzofuranol etheric compound with herbicidal activity and preparation method | HUNAN RES INST CHEMICAL IND | 2014-08-13 | — | — | CN | disclosed |
| EP-2760856-A1 | SELECTIVE NR2B ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2014-08-06 | — | — | EP | disclosed |
| US-8722670-B2 | Selective NR2B antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-04-17 | — | — | US | disclosed |
| EP-2700636-A1 | PROCESS FOR PREPARING EPISULFIDE COMPOUNDS | Asahi Kasei Chemicals Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| CN-103476764-A | Process for producing episulfide compound | ASAHI KASEI CHEMICALS CORP (JP) | 2013-12-25 | — | — | CN | disclosed |
| US-8513430-B2 | Substituted thiazol-2-ylamine derivatives, pharmaceutical compositions, and methods of use as 11-beta HSD1 modulators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8426437-B2 | Pyrroloquinoline derivatives and their use as protein kinases inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2013-04-23 | — | — | US | disclosed |
| US-20130085138-A1 | Selective NR2B Antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| WO-2013049119-A1 | SELECTIVE NR2B ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | WO | disclosed |
| CN-102070556-B | 5-benzyl-4-alkyl-2-aminothiazole as well as preparation and application of 5-benzyl-4-alkyl-2-aminothiazole | UNIV HUNAN | 2013-03-20 | — | — | CN | disclosed |
| EP-1686990-B1 | 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | US ARMY MED RES MAT COMMAND (US) | 2012-09-19 | — | — | EP | disclosed |
| CN-102603726-A | 5-(2-aminothiazole-4-yl) benzofuranol etheric compound with herbicidal activity and preparation method | HUNAN RES INST CHEMICAL IND | 2012-07-25 | — | — | CN | disclosed |
| CN-102010406-B | 4-(benzofuran-5-yl)-2-aromatic aminothiazole and preparation method and application thereof | UNIV HUNAN | 2012-07-04 | — | — | CN | disclosed |
| US-20120029029-A1 | SUBSTITUTED THIAZOL-2-YLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS 11-BETA HSD1 MODULATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2012015715-A1 | SUBSTITUTED THIAZOL-2-YLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS 11-BETA HSD1 MODULATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-02-02 | — | — | WO | disclosed |
| CN-102070556-A | 5-benzyl-4-alkyl-2-aminothiazole as well as preparation and application of 5-benzyl-4-alkyl-2-aminothiazole | UNIV HUNAN | 2011-05-25 | — | — | CN | disclosed |
| US-20110105436-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | AUCKLAND UNISERVICES LIMITED (NZ) | 2011-05-05 | — | — | US | disclosed |
| CN-102010406-A | 4-(benzofuran-5-yl)-2-aromatic aminothiazole and preparation method and application thereof | UNIV HUNAN | 2011-04-13 | — | — | CN | disclosed |
| US-7897720-B2 | Method for removing catalyst residues from polymer solution and polymers purified by the method | LG CHEM, LTD. (KR) | 2011-03-01 | — | — | US | disclosed |
| WO-2010086613-A1 | COMPOUNDS USEFUL AS INHIBITORS AS AMPK | BETAGENON AB (SE) | 2010-08-05 | — | — | WO | disclosed |
| CN-101768134-A | 2-imido-3-(substituted phenyl)-4-methyl-5-acetyl-4-thiazoline and synthesis method thereof | ZHEJIANG PHARMACEUTICAL COLLEG | 2010-07-07 | — | — | CN | disclosed |
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | disclosed |
| US-20100029900-A1 | METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD | LG CHEM, LTD. (KR) | 2010-02-04 | — | — | US | disclosed |
| WO-2009114552-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-09-17 | — | — | WO | disclosed |
| EP-1686990-A4 | 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | US ARMY MED RES MAT COMMAND (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2009-02-12 | — | — | US | disclosed |
| US-20080200371-A1 | THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | IMPINJ, INC. | 2008-08-21 | — | — | US | disclosed |
| WO-2008090356-A1 | THIAZOLIDINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND DISORDERS CAUSED BY EXCESS ADIPOSITY | BETAGENON AB (SE) | 2008-07-31 | — | — | WO | disclosed |
| US-7381736-B2 | Thiazole and thiadiazole inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| WO-2008056938-A1 | METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD | LG CHEM, LTD. (KR) | 2008-05-15 | — | — | WO | disclosed |
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| EP-1841749-A1 | DERIVATIVES OF THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | Metabasis Therapeutics, Inc. (US) | 2007-10-10 | — | — | EP | disclosed |
| CN-1919832-A | Method of preparing arylamine chloride by high selective catalytic hydrogenation of chlorine substituent aromatic nitro compound | UNIV DALIAN TECH (CN) | 2007-02-28 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | disclosed |
| US-7101902-B2 | 2-guanidinylimidazolidinedione compounds and methods of making and using thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-09-05 | — | — | US | disclosed |
| US-20060194768-A1 | Thiazole and thiadiazole inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2006-08-31 | — | — | US | disclosed |
| EP-1686990-A2 | 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | U.S. Army Medical Research and Materiel Command (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20060173096-A1 | Aqueous ink composition, and ink jet recording method and recorded matter using the same | SEIKO EPSON CORPORATION | 2006-08-03 | — | — | US | disclosed |
| WO-2006028970-A1 | DERIVATIVES OF THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| EP-1315714-B1 | QUINAZOLINE DERIVATIVES AS ALPHA-1 ADRENERGIC ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2005072082-A2 | 2-GUANIDINYLIMIDAZOLIDINEDIONE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20050148645-A1 | 2-Guanidinylimidazolidinedione compounds and methods of making and using thereof | ARMY, UNITED STATES | 2005-07-07 | — | — | US | disclosed |
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1315714-A2 | QUINAZOLINE DERIVATIVES AS ALPHA-1 ADRENERGIC ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| US-6559153-B2 | 1-(4-(((4-Amino-6,7-dimethoxy-quinazolin-2-yl)-methyl-amino) methyl)-4-phenyl-piperidin-1-yl)-1-cyclopropyl-methanone; treating disease states ameliorated by blockade of alpha-1 adrenoceptors; sleep/psychological disorders | SYNTEX (U.S.A.) LLC | 2003-05-06 | — | — | US | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| US-20020045614-A1 | Quinazoline derivatives as alpha-1 adrenergic antagonists | SYNTEX (U.S.A.) LLC | 2002-04-18 | — | — | US | disclosed |
| WO-2002018348-A2 | QUINAZOLINE DERIVATIVES AS ALPHA-1 ADRENERGIC ANTAGONISTS | F. HOFFMAN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | disclosed |
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| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |
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| EP-0535184-A1 | NOVEL QUINOLONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | BOUCHARA S.A. (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0533895-A1 | NOVEL QUINOLONES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOUCHARA S.A. (FR) | 1993-03-31 | — | — | EP | disclosed |
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| WO-1992015574-A1 | NOVEL QUINOLONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | BOUCHARA S.A. (FR) | 1992-09-17 | — | — | WO | disclosed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
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| US-4563533-A | FROM CORRESPONDING PHENYLTHIOUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4563533-A | FROM CORRESPONDING PHENYLTHIOUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282348-A1 | IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS | S100B, S100P, S100A4 | GAA 3238/4885MAPT 16/4885ALDH1A1 993/4885 |
| US-20050148645-A1 | 2-Guanidinylimidazolidinedione compounds and methods of making and using thereof | GUCY1B2, GUCY1A2, AGK | GAA 1153/4885MAPT 4699/4885ALDH1A1 677/4885 |
| US-10385069-B2 | Imidazo[2,1-B]thiazole and 5,6-dihydroimidazo[2,1-B]thiazole derivatives useful as S100-inhibitors | S100B, S100P, S100A4 | GAA 3238/4885MAPT 16/4885ALDH1A1 993/4885 |
| US-20130085138-A1 | Selective NR2B Antagonists | GRIN2B, GRIN2A, GRIN3A | GAA 1312/4885MAPT 1080/4885ALDH1A1 1942/4885 |
| US-20020045614-A1 | Quinazoline derivatives as alpha-1 adrenergic antagonists | ADRB1, ADRA1B, ADRA1D | GAA 2145/4885MAPT 2464/4885ALDH1A1 211/4885 |
| US-20110105436-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT | VHL, TP53, BECN1 | GAA 79/4885MAPT 2506/4885ALDH1A1 1737/4885 |
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | GAA 2365/4885MAPT 3318/4885ALDH1A1 961/4885 |
| US-20150197501-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | GAA 4338/4885MAPT 4698/4885ALDH1A1 405/4885 |
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | GAA 1149/4885MAPT 24/4885ALDH1A1 1731/4885 |
| US-20120029029-A1 | SUBSTITUTED THIAZOL-2-YLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS 11-BETA HSD1 MODULATORS | HSD11B1, HSD11B2, HSD3B1 | GAA 674/4885MAPT 2385/4885ALDH1A1 196/4885 |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | MAP3K1, MAP3K2, MAP3K7 | GAA 3035/4885MAPT 734/4885ALDH1A1 3830/4885 |
| US-20060194768-A1 | Thiazole and thiadiazole inhibitors of tyrosine phosphatases | PTPN1, PTPN5, PTPN18 | GAA 2114/4885MAPT 2035/4885ALDH1A1 1531/4885 |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | GAP43, NLN, SMN1; SMN2 | GAA 1149/4885MAPT 24/4885ALDH1A1 1731/4885 |
| US-20140107350-A1 | Process for Preparing Episulfide Compounds | TST, EPHX2, STS | GAA 4338/4885MAPT 4698/4885ALDH1A1 405/4885 |
| US-20080200371-A1 | THIAZOLE AND THIADIAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | PTPN1, PTPN5, PTPN18 | GAA 2114/4885MAPT 2035/4885ALDH1A1 1531/4885 |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | GAA 1149/4885MAPT 24/4885ALDH1A1 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.