Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976329 | 0.89 | SLC22A6 (0.46) | SLC22A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4976282 | 0.85 | PHF8 (0.52) | SLC22A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4979278 | 0.82 | SLC22A6 (0.48) | SLC22A6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4975915 | 0.80 | SLC22A6 (0.58) | SLC22A6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL12967662 | 0.76 | SLC22A6 (0.52) | SLC22A6ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4980899 | 0.76 | SLC22A6 (0.52) | SLC22A6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL12967769 | 0.76 | SLC22A6 (0.52) | SLC22A6ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL4975748 | 0.76 | SLC22A6 (0.52) | SLC22A6ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4978302 | 0.74 | SLC22A6 (0.50) | SLC22A6ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL23051809 | 0.73 | TSHR (0.60) | SLC22A6ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | claimed |