Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979808 | 0.85 | PHF8 (0.56) | LMNATSHRCYP1A2GABRR1NFKB1 | |
| SCHEMBL2510241 | 0.82 | SLC22A6 (0.48) | SLC22A6LMNATSHRTHRBBLM | |
| SCHEMBL4979278 | 0.82 | SLC22A6 (0.48) | SLC22A6LMNATSHRTHRBBLM | |
| SCHEMBL4975915 | 0.80 | SLC22A6 (0.58) | SLC22A6LMNATSHRTHRBBLM | |
| Succinic Acid SCHEMBL28081664 | 0.76 | LMNA (0.56) | SLC22A6LMNATSHRTHRBBLM | |
| SCHEMBL4977573 | 0.76 | SLC22A6 (0.52) | SLC22A6LMNATSHRKMT2ANPSR1 | |
| SCHEMBL4727560 | 0.76 | MAPT (0.52) | KMT2ANPSR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL28483121 | 0.76 | FAAH (0.38) | KMT2ANPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL12967769 | 0.76 | SLC22A6 (0.52) | SLC22A6LMNATSHRTHRBBLM | |
| SCHEMBL14895816 | 0.76 | CYP2D6 (0.48) | LMNATSHRTHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | claimed |
| WO-2016094846-A1 | INHIBITORS OF CELLULAR NECROSIS AND RELATED METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-06-16 | — | — | WO | disclosed |
| EP-0458327-B1 | Ureidoperoxycarboxylic acids, process for their preparation and their use | HOECHST AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5292451-A | For bleaching, oxidizing, or disinfecting | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5149864-A | Oxidation of uridocaroxylic acid derivative with hydrogen peroxide in presence of strong acidic catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
| EP-0458327-A1 | Ureidoperoxycarboxylic acids, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-27 | — | — | EP | disclosed |