Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975915 | 0.88 | SLC22A6 (0.58) | SLC22A6FOLH1KDM4EKDM6BKDM5C | |
| SCHEMBL4980094 | 0.86 | PHF8 (0.64) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL1261013 | 0.80 | FOLH1 (0.70) | SLC22A6FOLH1KDM4EKDM6BKDM5C | |
| SCHEMBL4976329 | 0.78 | SLC22A6 (0.46) | SLC22A6FOLH1KDM4EKDM6BKDM5C | |
| SCHEMBL4979704 | 0.78 | SLC22A6 (0.46) | SLC22A6FOLH1KDM4EKDM6BKDM5C | |
| SCHEMBL17828357 | 0.76 | LMNA (0.48) | SLC22A6FOLH1LMNATSHRNFKB1 | |
| SCHEMBL2813242 | 0.75 | HDAC1 (0.74) | SLC22A6FOLH1KDM4EKDM6BKDM5C | |
| SCHEMBL4980899 | 0.74 | SLC22A6 (0.52) | SLC22A6FOLH1KDM4EKDM6BKDM5C | |
| SCHEMBL4977573 | 0.74 | SLC22A6 (0.52) | SLC22A6KDM4ELMNATSHRNFKB1 | |
| SCHEMBL12967769 | 0.74 | SLC22A6 (0.52) | SLC22A6FOLH1KDM4EKDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | claimed |