Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451120 | 0.90 | PRKDC (0.34) | P2RX3ALDH1A1LMNATP53MAPT | |
| SCHEMBL5569978 | 0.90 | LMNA (0.38) | KDM4EALDH1A1HPGDLMNATP53 | |
| SCHEMBL5569980 | 0.90 | LMNA (0.38) | KDM4EALDH1A1HPGDLMNATP53 | |
| SCHEMBL4977432 | 0.90 | PRKDC (0.34) | P2RX3ALDH1A1LMNATP53MAPT | |
| SCHEMBL5566372 | 0.90 | PRKDC (0.34) | P2RX3ALDH1A1LMNATP53MAPT | |
| SCHEMBL5558310 | 0.89 | MAPT (0.39) | KDM4EHSD17B10ALDH1A1LMNATP53 | |
| SCHEMBL5566461 | 0.87 | KMT2A (0.39) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL5566458 | 0.87 | KMT2A (0.39) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL5329018 | 0.87 | KMT2A (0.37) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL5329027 | 0.87 | KMT2A (0.37) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326784-B2 | Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives | ALTANA PHARMA AG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-20070117786-A1 | Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives | ALTANA PHARMA AG (DE) | 2007-05-24 | — | — | US | disclosed |
| EP-1697358-A1 | INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC DIHYDROPYRANO -IMIDAZO -PYRIDINES DERIVATIVES | Altana Pharma AG (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058894-A1 | INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC DIHYDROPYRANO -IMIDAZO -PYRIDINES DERIVATIVES | ALTANA PHARMA AG (DE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117786-A1 | Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives | CYP1A1, CYP3A4, CYP19A1 | P2RX3 882/4885KDM4E 2425/4885HSD17B10 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.