Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329018 | 1.00 | KMT2A (0.37) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL5332664 | 1.00 | KMT2A (0.37) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL5566458 | 0.98 | KMT2A (0.39) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL5566461 | 0.98 | KMT2A (0.39) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL4977670 | 0.87 | P2RX3 (0.36) | ALDH1A1HPGDKDM4ETSHRNPC1 | |
| SCHEMBL4977432 | 0.83 | PRKDC (0.34) | ALDH1A1NPC1LMNARAB9ACXCR2 | |
| SCHEMBL5451120 | 0.83 | PRKDC (0.34) | ALDH1A1NPC1LMNARAB9ACXCR2 | |
| SCHEMBL5566372 | 0.83 | PRKDC (0.34) | ALDH1A1NPC1LMNARAB9ACXCR2 | |
| SCHEMBL5569978 | 0.83 | LMNA (0.38) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL5569980 | 0.83 | LMNA (0.38) | KMT2AMEN1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | claimed |
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |