Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 4/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261273 | 0.93 | HTR6 (0.59) | HTR6PFKFB3GHSRMLNRCYP2D6 | |
| SCHEMBL4971305 | 0.80 | HTR6 (0.54) | HTR6HTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL1576247 | 0.79 | HTR6 (0.55) | HTR6HTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL1575981 | 0.75 | HTR6 (0.85) | HTR6HTR1BHTR2AHTR2CHTR2B | |
| SCHEMBL1576283 | 0.74 | HTR6 (0.69) | HTR6HTR7HTR5A | |
| SCHEMBL1576109 | 0.74 | HTR6 (0.85) | HTR6HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL1575999 | 0.72 | HTR6 (0.68) | HTR6HTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL1576256 | 0.72 | HTR6 (0.68) | HTR6HTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL27694045 | 0.71 | HTR6 (0.56) | HTR6HTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL14014137 | 0.71 | PFKFB3 (0.62) | HTR6PFKFB3GHSRMLNRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |