Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.54 |
| ▸ | HTR1D | P28221 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 5/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR5A | P47898 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261273 | 0.87 | HTR6 (0.59) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL4977756 | 0.80 | HTR6 (0.50) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL4967568 | 0.77 | HTR6 (0.70) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL4970678 | 0.77 | HTR6 (0.61) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL7331855 | 0.75 | HTR1D (0.60) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL4967334 | 0.74 | HTR6 (0.74) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL3142938 | 0.73 | HTR6 (0.77) | HTR6HTR7HTR5A | |
| SCHEMBL4968621 | 0.73 | HTR6 (0.64) | HTR6HTR1DHTR1BHTR1A | |
| SCHEMBL4970935 | 0.72 | HTR6 (0.54) | HTR6HTR1DHTR1BHTR7HTR5A | |
| SCHEMBL8111937 | 0.72 | HTR1D (0.56) | HTR6HTR1DHTR1BHTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |