Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455315 | 0.88 | MAPT (0.77) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL2701432 | 0.86 | LMNA (0.64) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL3924451 | 0.85 | KMT2A (0.70) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL27731935 | 0.85 | MEN1 (0.69) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1454593 | 0.81 | MEN1 (0.72) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1454916 | 0.80 | LMNA (0.60) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1454500 | 0.79 | MEN1 (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1198183 | 0.79 | LMNA (0.58) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1454748 | 0.79 | MAPT (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7283173 | 0.78 | MAPT (0.69) | MEN1KMT2ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |