SCHEMBL49786

SCHEMBL49786

Cc1cccc(P(c2cccc(C)c2)c2cccc(C)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.61
ALDH1A1 P00352 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 2/20 0.45
TP53 P04637 1/20 0.42
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415924 1.00 ACHE (0.61) ACHEALDH1A1MAPK1TDP1CYP3A4
SCHEMBL5713327 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL29001481 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
Iodide SCHEMBL28418605 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
SCHEMBL18423870 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
Bromide SCHEMBL8849644 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
Bromide SCHEMBL6444894 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
SCHEMBL8849287 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL4529394 0.97 ACHE (0.58) ACHEALDH1A1MAPK1TDP1CYP3A4
Hydrochloric Acid SCHEMBL20454597 0.95 ACHE (0.55) ACHEALDH1A1MAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1938 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462342-B Method for effectively improving purity of linalool product 万华化学集团股份有限公司 2026-05-19 CN claimed
US-20250197356-A1 METHOD FOR SYNTHESIZING NUCIFERINE OR DERIVATIVE THEREOF, DERIVATIVE OF NUCIFERINE AND USE THEREOF HUAQIAO UNIVERSITY (CN) 2025-06-19 US claimed
CN-119842046-A Low-viscosity liquefied dicyandiamide latent curing agent, epoxy resin composition, and preparation method and application thereof 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-119613303-A Improved method for synthesizing and separating dimethyl thiotoluene diamine 江苏湘园化工有限公司 2025-03-14 CN claimed
CN-119462342-A Method for effectively improving purity of linalool product 万华化学集团股份有限公司 2025-02-18 CN claimed
CN-119192499-A Ethylene-butadiene polymer, process for producing the same, and vulcanized rubber 中国石油化工股份有限公司 2024-12-27 CN claimed
WO-2024262317-A1 METHOD FOR PRODUCING HYDROPHILIC QUANTUM DOT 信越化学工業株式会社 2024-12-26 WO claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
CN-118598913-A Organic cation onium salt blue light emitting material based on phosphine ligand, and preparation method and application thereof 中国科学院福建物质结构研究所 2024-09-06 CN claimed
CN-118373858-A Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-07-23 CN claimed
US-4929280-A Hydroformylation of carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-05-29 US claimed
US-4914157-A ADDITION OF HYDROFORMYLATED RUBBER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-04-03 US claimed
EP-0331593-A1 Process for the preparation of hydroxybenzaldehydes by hydrocarbonylation RHONE-POULENC CHIMIE (FR) 1989-09-06 EP claimed
US-4742137-A Polymer particles and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-05-03 US claimed
EP-0170456-A1 Polymer particles and process for producing the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-02-05 EP claimed
US-4538003-A TREATMENT WITH MAGNESIUM OR ZINC ORGANOMETALLIC REAGENTS IN PRESENE OF A NICKEL BIDENTATE OR TRIDENTATE PHOSPHOROUS LIGAND E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-27 US claimed
US-4414409-A Palladium sulfonate catalyst systems for carbonylation of olefins E. I. DU PONT DE NEMOURS & COMPANY (US) 1983-11-08 US claimed
US-4182813-A CATALYST COMPRISING A COBALT COMPOUND, ORGANOALUMINUM COMPOUND, AND AN ORGANIC PHOSPHORUS COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1980-01-08 US claimed
US-4176219-A COORDINATION CATALYST OF A COBALT AND PHOSPHINE COMPOUND, A TRIALKYLALUMINUM, WATER AND A HYDROCARBYL HALIDE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US claimed
US-4106936-A EXPOSURE TO ULTRAVIOLET RADIATION, HEATING TO FIX OR ERASE IMAGE XEROX CORPORATION (US) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197356-A1 METHOD FOR SYNTHESIZING NUCIFERINE OR DERIVATIVE THEREOF, DERIVATIVE OF NUCIFERINE AND USE THEREOF NUCB2, NISCH, CYP46A1 ACHE 1661/4885ALDH1A1 894/4885MAPK1 3193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.