Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524423 | 0.87 | LOXL2 (0.52) | LOXL2TSHRALDH1A1SNCAMAPT | |
| SCHEMBL4978604 | 0.87 | TSHR (0.46) | LOXL2TSHRALDH1A1SNCAMAPT | |
| SCHEMBL2135817 | 0.79 | ALDH1A1 (0.45) | TSHRALDH1A1SNCAMAPTCA12 | |
| SCHEMBL2768561 | 0.79 | TDP1 (0.58) | TSHRALDH1A1SNCAMAPTCA12 | |
| SCHEMBL5175273 | 0.79 | GPR35 (0.56) | LOXL2TSHRALDH1A1SNCAMAPT | |
| SCHEMBL2766494 | 0.79 | TDP1 (0.58) | TSHRALDH1A1SNCAMAPTCA12 | |
| Hydrochloric Acid SCHEMBL11086100 | 0.78 | LOXL2 (0.53) | LOXL2TSHRALDH1A1MAPTCA12 | |
| SCHEMBL1437048 | 0.78 | TSHR (0.47) | LOXL2TSHRALDH1A1SNCAMAPT | |
| SCHEMBL8832188 | 0.77 | GPR35 (0.58) | TSHRALDH1A1MAPTCA12TDP1 | |
| SCHEMBL13858882 | 0.77 | TSHR (0.44) | TSHRALDH1A1SNCACA12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190151-A1 | FLUORESCENTLY LABELED NUCLEOSIDE TRIPHOSPHATES AND ANALOGS THEREOF FOR SEQUENCING NUCLEIC ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2010-07-29 | — | — | US | disclosed |
| US-20070117104-A1 | Nucleotide analogs | FLUIDIGM CORPORATION | 2007-05-24 | — | — | US | disclosed |
| US-20070117103-A1 | Nucleotide analogs | FLUIDIGM CORPORATION | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117103-A1 | Nucleotide analogs | NT5C2, NT5C3B, NUDT1 | LOXL2 4724/4885TSHR 2431/4885ALDH1A1 2887/4885 |
| US-20070117104-A1 | Nucleotide analogs | NT5C2, NT5C3B, NUDT1 | LOXL2 4724/4885TSHR 2431/4885ALDH1A1 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.