Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | TACR3 | P29371 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977017 | 0.91 | NPC1 (0.36) | KDM4ECYP3A4 | |
| SCHEMBL4978494 | 0.88 | NPC1 (0.34) | KDM4ESMN1; SMN2 | |
| SCHEMBL4977389 | 0.87 | ALDH1A1 (0.33) | PTPN1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4975463 | 0.83 | NPC1 (0.36) | KDM4ECYP3A4 | |
| SCHEMBL2725437 | 0.80 | NPC1 (0.36) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL714505 | 0.75 | NPC1 (0.46) | KDM4ESMN1; SMN2 | |
| SCHEMBL4974243 | 0.73 | NPC1 (0.33) | — | |
| SCHEMBL29706519 | 0.71 | HTT (0.35) | KDM4EMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL708477 | 0.71 | HTT (0.35) | KDM4EMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL29362516 | 0.71 | NPC1 (0.48) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131921-A1 | SILYLATED, SUBSTITUTED BENZOTRIAZOLYLPHENOL COMPOUNDS | ISDIN S.A. (ES) | 2008-11-06 | — | — | WO | claimed |
| WO-2008131921-A1 | SILYLATED, SUBSTITUTED BENZOTRIAZOLYLPHENOL COMPOUNDS | ISDIN S.A. (ES) | 2008-11-06 | — | — | WO | disclosed |